Molecular materials have been a subject of interest in fundamental research and applications for decades, and have been studied as bulk crystals, (thin) films and as individual molecules, due to the large variety in their properties. This dissertation explores pentacene crystals near the two-dimensional…

Natural resources often stretch across borders that separate modern nation states. This can create conflict and limit opportunities for regulated consumption of their goods and services, but also provide opportunities for joint multinational efforts that exceed single country capabilities.

Schistosomiasis is an acute and chronic disease caused by blood dwelling parasitic trematodes of the genus Schistosoma, and it is classified as the second most socioeconomically devastating parasitic disease, second only to malaria.

The overarching goal of this thesis is to set the foundations, but also make the first essential steps towards establishing a comprehensive, mesoscopic, hydrodynamic theory of epithelial tissues. The stage is set by an exhaustive study of topological defects in passive p-atic liquid crystals, singularities…

Radiography is an important technique to inspect objects, with applications in airports and hospitals. X-ray imaging is also essential in industry, for instance in food safety checks for the presence of foreign objects.

A key step in the synthesis of oligosaccharides and glycoconjugates is the formation of the glycosidic bond.

The different kinds of cultural perspectives on health and disease of the participants are related to their knowledge, beliefs, values and practices manifested in various forms of lifestyle in Indonesia. The cultural diversity of the population is also related to differences in health behaviour.

Promotor: H.W. Lenstra

Promotor: Thomas Hankemeier, Co-promotores: Heiko van der Linden, Paul Vulto

More than 5,000 exoplanets have been found over the past couple of decades. These exoplanets show a tremendous diversity, ranging from scorching hot Jupiters, common super-Earths, to widely separated super-Jupiters on the planet/brown dwarf boundary.

This thesis discusses the physical and chemical processes than influence the composition of forming planets.

Promotor: Prof.dr. H.J.A. Rottgering

Aspergillus niger is an important industrial producer of organic acids and enzymes producing large amounts of spent fungal biomass.

Promotor: J. Aarts

In this thesis integral points on affine del Pezzo surfaces are studied.

Streptomyces present a valuable platform for natural product discovery. Lugdunomycin is a novel angucycline-derived polyketide from Streptomyces sp QL37, with unprecedented skeleton and antimicrobial activity.

We have conducted a full spectral line survey of the 3-13 micron region of two massive protostars, AFGL 2591 and AFGL 2136, for the first time at high spectral resolution.

In this thesis, we develop a novel technique called Optical Near-field Electron Microscopy (ONEM), which aims to combine the advantages of both optical and electron microscopy: the high resolution of electron microscopy and the low sample damage of optical microscopy.

Promotor: Bas Edixhoven, Promotor: Qing Liu

This thesis tackles the difficulty of predicting the liver’s clinical response to novel therapies, a challenge arising from interspecies differences and limitations of existing in vitro models.

Promotores: P.G.L. Klinkhamer, P.M. Brakefield, Co-Promotor: M. Bruinsma

Supervisor: P.J.J. Hooykaas

Human language is constantly evolving with its linguistic structure being shaped by language users at both individual and population levels. Focusing on the interplay between processes of language acquisition and communicative need in shaping human languages, this thesis introduces a novel computational…

Plants produce an astonishing variety of secondary metabolites (SMs) which are thought to play vital roles in the fitness of plants through ecological interactions.

Salicylic acid (SA) is a plant hormone, which is involved in the defense responses to pathogens and to abiotic stress, and in the regulation of plant growth and development.

Promotor: Prof.dr. P.C. van Welzen

Plastics have become an integral part of modern society due to their versatility and durability.

Lezing

Lezing

The global transition toward low-carbon energy systems and the rapid expansion of digital technologies, including artificial intelligence, are reshaping how modern societies produce, move, and process energy and information.

Preterm birth is a major contributor to neonatal morbidity and mortality and is associated with both acute complications and long-term health consequences.

Lezing

Promotores: T.H. Oosterkamp, N. de Jonge

In populations with a seed-bank, individuals can temporarily become dormant and refrain from reproduction until they can become active again. The repository of all dormant individuals in the population is called the seed-bank. Seed-banks are observed in many taxa, including plants, bacteria and other…

For each living organism health is ensured by correct functioning of its cells. Cells therefore have elaborate methods for regulation of their proteins.

Over the last three decades, the discovery of exoplanets has revealed the boundless variety of worlds beyond our own Solar System⁠. Majority of planetary systems contain short-period planets that are larger than Earth but smaller than Neptune⁠.

Promotor: Prof.dr. G.R. de Snoo, Co-promotor: R. Heijungs

Bent u geïnteresseerd in samenwerken met de Universiteit Leiden of met het LUMC?

Environmental challenges such as plastic pollution and biodiversity loss require extensive monitoring. Citizen science, in which members of the public participate in scientific research, has therefore become an important approach in environmental science.

This thesis investigates innovative and classical strategies in glycoconjugate vaccine development to address the growing threat of multidrug-resistant bacterial infections.

In Israël is bij een opgraving van een synagoge bij Horvat Kur een prachtige ingelegde vloer blootgelegd. In de verweerde steentjes van het gevonden mozaïek staat nog duidelijk de naam ‘El’azar’ the lezen. Leidse onderzoeker Jürgen Zangenberg was samen met een groep studenten betrokken bij de opgraving.…

How can data analytics be used as a research method in the field of legal research? This question was addressed during the Research Lab Legal Data Science on 23 September, 2016.

Van de tanden van apen tot de microstructuur van botten: archeologe Simone Lemmers (31) is gefascineerd door botresten die ons meer vertellen over het verleden. Haar nieuwsgierigheid heeft geleid tot een zeer internationale carrière. Via het Verenigd Koninkrijk, waar ze getuige was van het Brexit-referendum,…

In the past decade many population studies have been performed with the Atacama Large Millimeter/submillimeter Array (ALMA) to understand the bulk properties of protoplanetary disks around young stars. These population studies mostly consisted of low mass stars, with relatively few of the disks around…

There is an urgent need for more physiologically relevant cell culture methods to guide compound selection in pre-clinical stages of the drug development pipeline.

Hoe positioneerde onze academische gemeenschap zich ten opzichte van een systeem dat mensen van hun vrijheid beroofde? Welke rol heeft de universiteit als onderwijsinstelling ingenomen ten opzichte van kolonialisme en het slavernijsysteem? Hoe kunnen wij het beste omgaan met onze bijzondere collecti…

Leonor Álvarez Francés heeft de Essayprijs 2016 van het Huizinga Instituut gewonnen. Het instituut schreef de essaywedstrijd over nieuwe technologie en cultuurwetenschappen eerder dit jaar uit.

Als docent op de Johan de Wittschool ben je dagelijks getuige van een microgemeenschap waarin grote verschillen voorkomen, en daaruit voortvloeiende conflicten. Dat stelt Matthias Schotanus, student van het Leiden University College en deelnemer aan het Community Project ‘Engage The Hague’. Op 2 juni…