In this thesis an activity-based probe was discovered that could visualize the activity of PLAATs. With an optimized gel-based ABPP assay in hand, screening of a compound library led to the discovery of alpha-ketoamides as a hit for PLAAT3.

S.S. Kolipaka’s thesis questions and investigates the survival prospects of reintroduced tigers and their offspring’s in the human dominated landscape of Panna tiger reserve in India.

Het Leids Universitair Centrum voor de studie van Islam en Samenleving (LUCIS) is een interfacultair kenniscentrum dat een multidisciplinaire en vergelijkende benadering van islam en moslimsamenlevingen bevordert.

Glucocorticoids (GCs) are widely prescribed as anti-inflammatory drugs due to their well-established immunosuppressive effects.

Promotor: J.W. van Holten

The solar system was formed approximately 4.56 billion years ago. Despite the numerous theories that have been developed over the years, the formation and evolution of the solar system still remain unclear.

This thesis investigates how galaxies form and what diversifies the evolutionary histories of galaxies.

In recent decades, climate change has led to more frequent and severe drought events, causing serious consequences such as increased forest mortality and significant crop yield losses. Understanding how drought affects plants, especially economically important herbaceous species, is crucial for predicting…

Promotores: B. Erez, P. Stevenhagen, Co-Promotor: B. de Smit

Op 12 januari 2022 verdedigde Mirjam Franke het proefschrift 'Over de grens van de onrechtmatige daad'. Het promotieonderzoek is begeleid door prof.mr. A.G. Castermans en prof.mr. J.H. Crijns.

In this thesis, a system pharmacology approach, integrating metabolomics, pharmacology and chemical biology, was applied to understand and modulate the endocannabinoid system across different model systems (cells, zebrafish, mice and humans).

An important part of the SCS specialisation is the internship period. Students will get the opportunity to get to know the field and to apply what they have learned during the courses.

Promotor: G.R. de Snoo, Co-promotor: H.H. de Iongh, C.J.M. Musters

Promotor: M. Franx, Co-Promotor: I.F. Labbé

Promotor: M.A.G.J. Orrit

Promotores: J. Kok, M. Chaudron (Chalmers University)

Promotor: Prof.dr. J.W.M. Frenken

Promotor: Prof.dr. E. Bouwman, Co-Promotor: S. Bonnet

The endophytic microbiota is a community of various microorganisms that reside in plant tissue. These microbes are known to promote plant health and resilience, and their members do not simply exist side by side.

Voor studenten kan studeren in Den Haag het verschil maken. Den Haag draagt met trots de titel ‘internationale stad van vrede en recht’. Den Haag biedt volop kansen en is een geweldige studentenstad.

During the development of the (human) body from a single fertilized egg, organs and structures must form. The development and growth of biological forms is called morphogenesis.

Studying the impact of urbanisation on the respiratory health of past Dutch populations (1200-1850 CE).

Het menselijk brein slaat niet alleen losse woorden op, maar ook allerlei abstractie informatie over die woorden. Sprekers hebben daar bovendien actief toegang toe, blijkt uit onderzoek van Leidse taalkundigen.

Onderzoekreeks van de Afdeling Economie van de Universiteit Leiden op het raakvlak van economie en recht.

This thesis focuses on the study of transient and variable radio sources in the universe.

De voorgestelde beleidsmaatregelen zijn het resultaat van een interactief proces tussen medewerkers, studenten, de D&I adviesgroepen, externe experts en het Expertisebureau D&I.

We show that Kirchhoff ’s law of conservation holds for non-commutative graph flows if and only if the graph is planar. We generalize the theory of (Euclidean) lattices to infinite dimension and consider the ring of algebraic integers as such a lattice.

Promotor: Prof.dr. C.U. Keller

Single-Molecule Microscopy (SMM) techniques constitute a group of powerful imaging tools that enable researchers to study the dynamic behavior of individual molecules.

Promotores: H.W. Lenstra, B. Erez, Co-promotor: L. Taelman

We describe certain birational modifications of nodal relative curves over a regular base of arbitrary dimension.

Met het onderzoek ‘Baby’s eerste hapjes’ willen wij meer te weten komen over de overgang naar vast voedsel bij baby’s. Zo zijn we benieuwd hoe de overgang naar vast voedsel bij kinderen verloopt, hoe het eetpatroon van kinderen zich na de overgang verder ontwikkelt en hoe ouders deze overgang en het…

Migration imposes special pressures on the meaning, experience and organization of lifecycle rituals. These pressures are felt most strongly by Muslim migrants to Western Europe. In this innovative study, Nathal M. Dessing examines the effects of migration on the life cycle rituals of Moroccan, Turkish…

This thesis consists of three chapters. Each chapter is on a different subject. However, all three chapters address issues that arise in counting arithmetically interesting objects.

Khadija Kadrouch-Outmany defended her thesis on 16 Septem ber 2016.

Promotor: A. Doelman, Co-promotor: M.F.E. de Jeu

Mechanical interactions between cells and their environment play an important role in many biological processes.

Promotores: Prof.dr. F.P. Israel, Prof.dr. P.P. van der Werf

In this thesis, I study 1) metabolic alterations in tuberculosis related to wasting syndrome in human patients as well as in rodent and fish animal models. 2) effects of the mutation of the leptin gene on cachexia and diabetes in rodent and zebrafish animal models.

Neuraminidases are enzymes that cleave glycosidic linkages of sialic acid. These enzymes are involved in influenza infections as well as in many cellular processes in mammals and micro-organisms.

Promotor: Prof.dr. P. Stevenhagen, Co-Promotor: J.H. Evertse

This thesis is an experimental study of the UV irradiation of the interstellar ice analogues, relevant for the different stages of the star and planet formation sequence.

-

In this thesis we examine certain phenomena in symplectic topology which are related to the theory of isolated singularities.

Promotor: W.Th.F. den Hollander