Solar energy harnessed by plants and algae has great potential to be converted into biofuels for future generations.

Promotor: Prof.dr. P.G.L. Klinkhamer, Co-Promotor: T.J. de Jong

Promotor: K.J. Batenburg, Co-promotor: A.W. van der Vaart, B. de Smit

Promotores: Prof.dr. H. van Veen & Prof.dr. W. de Boer (Wageningen University)

Promotor: Koen Kuijken Co-promotor: Henk Hoekstra

The effective treatment of tuberculosis (TB) remains a major challenge to global health.

Streptomyces bacteria are a valuable source of natural products, many of which are used in the clinic or in biotechnology.

Promotor: J.N. Kok, Co-Promotor: A.J. Knobbe

Endothelial dysfunction and microvascular diseases are key drivers of cardiovascular disease, the world's leading cause of death.

Promotors: C.A.J. Knibbe, Anthonius de Boer, Co-promotor: M.M.J. van der Vorst

Promotor: T. Schmidt, Co-promotor: S. J.T. van Noort

At the largest scales, two ingredients dictate the distribution of matter in the Universe. The first is dark matter, acting as an invisible scaffolding held together by gravitational forces.

The increasing resistance of pathogenic bacteria to antibiotics necessitates the discovery of new medicines.

Prematurely born neonates require, amongst others, pharmaceutical therapy. Dosing guidelines for these therapies are often based on data from term born neonates or older infants, while these are not necessarily similar to prematurely born neonates.

Promotor: Prof.dr. B.R. Katzy

Promotor: Prof.dr. T. Hankemeier, Co-promotor: Theo Reijmers

This thesis aims to investigate the effect of tripartite interaction between microbial inoculants, the plant, and herbivore insects on the rhizosphere microbiome and volatilome. We investigated the rhizosphere microbiome and volatilome of tomato plants exposed to insect herbivory and/or inoculated with…

Promotor: Prof.dr. B. van de Water

Promotor: Prof.dr. J.N. Kok, Co-promotor: A.J. Knobbe

Stars and planets form within cold, dense clouds of gas and dust drifting through interstellar space. Although dust makes up only a small fraction of this material, it plays a key role in shaping the chemical evolution of these environments.

In this Ph.D. thesis, we characterized two novel upstream regulators of JUB1, HB40, and HB22, in Arabidopsis thaliana. In Chapter 2, we described functions of HB40 in modulating growth and development via the regulation of JUB1 and GA inactivation genes GA2OXs.

Stars like the sun are born in large molecular clouds existing from gas and dust. During the formation process, the chemical composition of the material can be altered drastically by the changing physical conditions.

Plants and soils from natural ecosystems harbor great diversity of soil microorganisms, which could potentially contribute to the sustainability of horticulture. The knowledge about using wild plant species and soil from natural ecosystem to improve the crop health will advance the application of ecological…

This dissertation focuses on developing new mathematical and statistical methods to properly represent time-varying covariates and model them within the context of time-to-event analysis.

This thesis focuses on the X-ray spectral analysis of merging galaxy clusters and the plasma code development for future high-resolution X-ray spectroscopy observations.

Promotores: G. Persoon, R. Schefold

The filamentous bacteria Streptomyces are widespread inhabitants of terrestrial soils.

Promotor: R. Cramer

Promotor: Bas Edixhoven, Promotor: Qing Liu

This thesis tackles the difficulty of predicting the liver’s clinical response to novel therapies, a challenge arising from interspecies differences and limitations of existing in vitro models.

Plants produce an astonishing variety of secondary metabolites (SMs) which are thought to play vital roles in the fitness of plants through ecological interactions.

This thesis explores how bees and hoverflies are distributed across the Dutch landscape and how ecological and landscape factors shape their occurrence.

This collection of papers was compiled in celebration of the remarkable academic career of Professor Wil Roebroeks, who has established himself as one of Europe’s leading figures in Palaeolithic archaeology over the past three decades and founded the Human origins research group at Leiden University…

Promotor: S.J. Edixhoven, Co-promotor: R.S. de Jong

This thesis investigates Open-world Continual Learning (OWCL), a learning paradigm designed for intelligent systems operating in non-stationary environments with persistent exposure to unknown data.

Preterm birth is a major contributor to neonatal morbidity and mortality and is associated with both acute complications and long-term health consequences.

Drug development critically depends on preclinical models that mimic human physiology, yet traditional two-dimensional cultures and animal models often lack predictive power.

Over the past two centuries, socioeconomic development has improved material living standards but has also intensified environmental pressures, including climate change and biodiversity loss.

Conventional food supplies procured from rural areas are increasingly vulnerable to disruptions caused by extreme weather, geopolitical instability, and logistical bottlenecks.

In dit interdisciplinaire onderzoeksprogramma werken onderzoekers uit vijf verschillende disciplines met elkaar samen. Zij stellen zich hieronder (in het Engels) aan u voor.

The work described in this thesis focuses on the development of linear or cyclized peptide probes against protein N-methyltransferases to characterize their specific binding behavior, providing further binding details for inhibitory activity study.

The aim of this thesis is to present novel techniques for proving cryptographic schemes secure against quantum adversaries. Most results are within the context of an idealized model called the ‘quantum random-oracle model’.

In this top-rated course, you will learn how the European Union prepares and decides on policy, and how policy is transferred to member states and implemented by various authorities. It discusses the challenges of the European multi-level governance structure and the main causes of policy failure or…

Tijdens de dies voor alumni op zaterdag 10 februari 2018 heeft Vincent Bakker de tweede prijs van de Leidse Universitaire Scriptieprijzen 2018 in ontvangst genomen. Deze prijzen worden mogelijk gemaakt door het Fonds Minerva Reünisten Jaar 1957/1961/1965, ondergebracht bij het Leids Universiteits Fonds…

Om talent aan te trekken en te behouden, bieden kantoren op de Zuidas ondersteuning aan (toekomstige) ouders. Zo voorzien zij steeds vaker in bijvoorbeeld slaapcoaches, een oppas en fertiliteitstrajecten. Hoogleraar economie Olaf van Vliet duidt deze ontwikkeling in het FD.

Politieke partijen willen de arbeidsmigratie terugdringen zonder de Nederlandse economie te schaden. Maar is dat wel mogelijk? Hoogleraar Economie Olaf van Vliet sprak met de NOS over de afwegingen en gevolgen van beperkende maatregelen.

Immigranten verdienen in Nederland gemiddeld 15 procent minder dan collega’s zonder migratieachtergrond, blijkt uit nieuw onderzoek. Olaf van Vliet, hoogleraar Economie, verklaart deze loonkloof in de Volkskrant.

Olaf van Vliet behoort tot de vier hoogleraren gespecialiseerd in migratie die worden benoemd tot Leiden-Delft-Erasmus-hoogleraar.

Het College van Bestuur heeft Olaf van Vliet benoemd tot hoogleraar economie aan de Universiteit Leiden, met als specialisatie sociale zekerheid en arbeidsmarktbeleid in internationaal perspectief. Deze leerstoel is verbonden aan zowel de Afdeling Economie (Faculteit der Rechtsgeleerdheid) als aan het…

Toen AFAS aankondigde dat hun werknemers vier dagen gingen werken voor hetzelfde fulltime salaris, vroegen veel mensen zich af: kan dat zomaar? Hoogleraar Olaf van Vliet sprak met Trouw en Nu.nl over de uitdagingen van dit model.