Nanoparticles can be used as delivery systems for both small molecules and macromolecules such as proteins, peptides or oligonucleotides. This thesis focuses on the use of liposomes, nanometric vesicles formed by a lipid bilayer enclosing an aqueous core. Liposomes are highly versatile delivery syst…

Promotor: C.A.M.J.J. van den Hondel, Co-promotor: Sandra de Weert

Synthetic hydrogels that mimic the natural extracellular matrix in the biophysical and biochemical cues it provides to cells are in high demand, however the cell phenotypes as they are observed in vivo in numerous cases have yet to be attained.

Promotor: F.S. de Boer, Co-promotor: M.M. Bonsangue

Announcement of a new publication by Janneke Verheijen, lecturer at the Institute of Cultural Anthropology and Development Sociology.

To this day, all cyclophellitol-based inhibitors and ABPs have been close analogues of their natural substrate counterparts. As a result, these probes showed high selectivity towards their target glycosidases.

This dissertation explores how we can make anomaly detection—identifying unusual or faulty behavior in complex systems—more trustworthy and effective, with a focus on smart manufacturing.

An important part of the SCS specialisation is the internship period. Students will get the opportunity to get to know the field and to apply what they have learned during the courses.

CONSENT (Consumer sentiment regarding privacy on user generated content services in the digital economy) is a research project funded by the European Union under the 7th Framework Programme. The question central to this research is whether recent changes to consumer and commercial practices developed…

Multicopper oxidase, laccase, can efficiently reduce oxygen to water and are mostly used in the enzymatic biofuel cells.

The soil ecosystem consists of the largest reservoir of biodiversity on Earth.

Promotores: H.W. Lenstra, A. Lucchini

Op 16 juni 2020 verdedigde Andrea Varga haar proefschrift 'Establishing State Responsibility in the Absence of Effective Government'. Het promotieonderzoek is begeleid door promotoren prof. dr. N.J. Schrijver en prof. dr. F. Baetens (University of Oslo).

Bacteria often experience external challenges, such as changes in environmental conditions or attacks by bacteriophages.

Promotor: M.A.G.J. Orrit

Promotores: Prof.dr. T.H.W. Bäck, Prof.dr. M. Bongards (Cologne University)

Promotor: S.M. Verduyn Lunel, Co-Promotores: S.C.Hille, O.W. van Gaans

Nanodiscs are small, disc-shaped structures designed to mimic biological cell membranes, composed of a lipid bilayer stabilized by scaffold proteins. Membrane proteins play crucial roles in essential processes such as nutrient and waste transport, molecular recognition, and cell signalling, making them…

Soil is a home for an unbelievable diversity and abundance of microbial life that is essential for supporting life on our planet.

This thesis takes steps toward understanding the interaction between gas-phase and solid-state molecules in star- and planet-forming regions.

Promotores: Prof.dr. J. A. Bouwstra, Prof.dr. W. Jiskoot

The intradermal administration route is attractive for vaccine delivery, because of the highly populated antigen-presenting cells in the skin. However, the skin’s main physical barrier, the stratum corneum, prevents vaccines from entering the skin.

The thesis addresses the long-term dynamical evolution of hierarchical multiple systems.

This thesis was embedded in the APELAFICO project and focussed on investigating effects of sound from North Sea offshore wind farms on pelagic fish and harbour porpoise.

Adenosine diphosphate ribosylation (ADP-ribosylation) is a fascinating post-translational modification (PTM) that plays a role in a variety of cellular processes and is associated with several diseases, including cancer and viral infections.

The project

Learning a programming language is challenging. Even one of the first –but crucial– concepts to learn, variables, is hard to grasp. Variables can represent different roles and functions within a code and need to be named appropriately to support code comprehension and debugging.

Faciliteiten waar LIBC leden gebruik van kunnen maken (in het Engels):

Hieronder vind je een overzicht van alle PRE-Classes die door de verschillende opleidingen van de Universiteit Leiden worden verzorgd. Bij elk onderdeel kun je een inhoudelijke beschrijving vinden en meer specifieke informatie over de eisen die aan deelname aan de betreffende Class verbonden zijn.

A neurocognitive investigation of the development of social performance monitoring in youth growing up in stressful versus non-stressful environments

The research presented in this thesis concerns one of the most important questions in software engineering of our time: how can we make sure that software is free from memory safety bugs?

The research in this dissertation aims to optimise blood donation processes in the framework of the Dutch national blood bank Sanquin. The primary health risk for blood donors is iron deficiency, which is evaluated based on donors' hemoglobin and ferritin levels.

Het belangrijkste doel van dit onderzoek is om de steden van het Romeinse Nabije Oosten in de keizertijd in kaart te brengen, met een focus op locatie, stadsgrootte en stedelijke kenmerken, om de vorm van het stedelijke systeem en de niveaus van integratie te bestuderen.

Promotor: Richard D. Gill

Subproject of the ERC project 'Challenging the Liberal World Order from Within: The Invisible History of the United Nations and the Global South'.

What is the optimal design of sandy solutions for sustainable climate change adaption, from an ecological, biophysical and societal point of view?

Workshop

Kunst en vrije tijd, Kunst en vrije tijd

Workshop

Studievoorlichting, Student for a Day

Studievoorlichting, Student for a Day

At the faculty of Governance and Global Affairs we are proud to celebrate social entrepreneurship, which is why we decided to introduce you to an amazing project by two of our students: Kimberly Schoenmaker and Caroline Flohr. Ambitious, driven and incredibly conscious of the corporate responsibility…

Arbeidsmigratie is een belangrijk thema voor de Tweede Kamerverkiezingen eind deze maand. Olaf van Vliet, hoogleraar Economie, sprak met de NOS over de beleidsmatige keuzes die arbeidsmigratie terug kunnen dringen.

Mocht de PVV bij de Tweede Kamerverkiezingen van 15 maart a.s. als grootste partij uit de stembus komen, moet zij dan – zoals de staatkundige conventie dat wil - ook het initiatief krijgen in de kabinetsformatie?

Één vraagstuk, bekeken vanuit één vakgebied door twee wetenschappers verbonden aan één en hetzelfde instituut—dat levert twee posities op. De Leidse politicologen Ruud Koole en Joop van Holsteyn gingen in het dagblad Trouw (zaterdag 22 oktober 2016) met elkaar in debat over de komende lijstrekkersverkiezingen…

De polarisatie in onze samenleving neemt toe. Waardoor worden mensen steeds radicaler? Hoe beschermen we onszelf tegen extremistische, terroristische of criminele dreiging, of deze nu fysiek of in de cyberwereld speelt? En welke rol spelen inlichtingendiensten hierin?

Binnen dit instituut wordt veel gevangenisonderzoek verricht. Detentie is de strengste sanctie die in de strafrechtstelsels van de Europese landen wordt toegepast.

Promotie

Dit was het programma van De Kennisboomgaard 2025:

Participants in this course will learn to support student teachers and new colleagues in their professional development as teachers, with particular emphasis on the context of bilingual or international education, as in the ICLON World Teachers Programme (WTP).