3,985 zoekresultaten voor “leiden teacher academic” in de Publieke website
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Study Information Committee
The Study Information Committee works to create a positive and accurate picture of the bachelor and master programs offered by the Institute of Biology Leiden (IBL). The committee consists of IBL staff members and study ambassadors. We reach out to future and current students, high school biology teachers,…
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Gerhard BurgerFaculteit der Wiskunde en Natuurwetenschappen
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Topological decoding of biomolecular fold complexity
Biological polymers, including proteins and the genome, undergo folding processes crucial for their proper functioning. Even slight changes in the folding structure of these biopolymers can have significant implications, leading to the development of various pathological conditions, such as neurodegenerative…
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Bio-Pharmaceutical Sciences (MSc)
Deze opleiding wordt aangeboden door het Leiden Academic Centre for Drug Research en is gericht op onderzoek en ontwikkeling van geneesmiddelen. Het programma beslaat vrijwel het gehele gebied van het geneesmiddelenonderzoek en biedt studenten veel keuzevrijheid.
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Liposomes as delivery system for allergen-specific immunotherapy
In this book liposomes are explored as delivery system for allergen-specific immunotherapy. Both cationic and anionic formulations are prepared with Bet v 1, one of the allergens in birch pollen.
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The impact of non-genetic factors on drug metabolism: towards better phenotype predictions
This thesis investigates how non-genetic factors, such as inflammation and concomitant medication, impact hepatic drug metabolism and subsequent drug metabolizing phenotype predictions.
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Global metabolomics and lipidomics approaches to probe virus-host interactions
The outbreaks of AIDS and COVID-19 showed clearly how infectious viruses can influence people’s lives. Investigating the changes in the host metabolism may provide a paradigm shift to consider immune-metabolic interactions as therapeutic targets.
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Genomics driven metabolomics novel strategies for the discovery and identification of secondary metabolites
Promotor: T. Hankemeier, Co-promotor: R.J. Vreeken
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Composition and function of integrin adhesions
Integrins play an essential role in multicellular life by connecting cells to the extracellular matrix.
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Profielwerkstukken
Voor je profielwerkstuk (PWS) ga je een eigen onderzoek doen. Een mooie voorbereiding op je latere studie! Wil je meer weten over hoe je dat aanpakt, of zoek je nog naar een onderwerp? Het Loket Profielwerkstukken biedt hulp in de vorm van informatie en inspiratie. Je kunt ons ook vragen stellen.&nb…
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Blueprints of Disease: Precision Platforms for Modelling Breast Cancer
Promotie
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How nutrient conditions shape antibiotic sensitivity in Pseudomonas aeruginosa
The impact of the phenotypic plasticity of P. aeruginosa and the distinct CF lung microenvironments on antibiotic drug effects and resistance remains poorly understood.
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Individualization of Drug Clearance Predictions and Dose Regimens in Patients with Obesity Using Pharmacometric Approaches
Promotie
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Visiting scholars
We verwelkomen gastwetenschappers wier onderzoek aansluit bij onze uiteenlopende expertisegebieden. De tekst gaat verder in het Engels.
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Lisann BrinckerFaculteit der Wiskunde en Natuurwetenschappen
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Marit PostmaFaculteit der Wiskunde en Natuurwetenschappen
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Hanne Cuyckens en Daan Weggemans benoemd tot Teaching Fellow
Hanne Cuyckens en Daan Weggemans zijn per 1 september 2023 benoemd tot Teaching Fellow en lid van de Leiden Teachers’ Academy (LTA).
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Eregalerij 2020
Ook in 2020 hebben veel van onze medewerkers en studenten mooie prijzen gewonnen en belangrijke onderzoekssubsidies binnengehaald.
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Connect & Disclose the use of generative AI with the FAIR AI Attribution (FAIA) framework
Webinar with Q&A
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New Foundations for Separation Logic
The research presented in this thesis concerns one of the most important questions in software engineering of our time: how can we make sure that software is free from memory safety bugs?
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Onderzoek
Onderzoekers vanuit verschillende vakgebieden werken samen om oplossingen te bedenken voor maatschappelijke problemen.
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Studentenleven
Ontdek het studentenleven bij de MSc Political Theory: Legitimiteit en Rechtvaardigheid aan Universiteit Leiden: studieverenigingen, activiteiten, academische gemeenschap en wonen in Leiden en Den Haag.
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Picturing Scholasticide: The Future of Higher Education in Palestine
Hoe beïnvloedt de vernietiging van universiteiten in Gaza, ook wel 'scholasticide' genoemd, het wetenschappelijk leven en wat zijn de theoretische en juridische onderbouwingen van de term?
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Taalklavertje vier
Het Taalklavertje vier is een didactische handreiking voor leerkrachten Engels op school, pabo-opleiders Engels en pabo-studenten, met videovoorbeelden op dvd.
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Shakespeare Sonnets & Soliloquies (English spoken)
Kunst en vrije tijd, Kunst en vrije tijd
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Over de opleiding
Met de universitaire lerarenopleiding behaal je een eerstegraads onderwijsbevoegdheid om docent te worden in het voortgezet onderwijs.
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Over de opleiding
Met de universitaire lerarenopleiding behaal je een eerstegraads onderwijsbevoegdheid om docent te worden in het voortgezet onderwijs.
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Over de opleiding
Met de universitaire lerarenopleiding behaal je een eerstegraads onderwijsbevoegdheid om docent te worden in het voortgezet onderwijs.
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Over de opleiding
Met de universitaire lerarenopleiding behaal je een eerstegraads onderwijsbevoegdheid om docent te worden in het voortgezet onderwijs.
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Over de opleiding
Met de universitaire lerarenopleiding behaal je een eerstegraads onderwijsbevoegdheid om docent te worden in het voortgezet onderwijs.
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Alumni
Sinds 2009 behaalden 95 kandidaten hun doctoraat in Creative en Performing Arts. Op deze pagina een overzicht van ACPA's alumni.
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The academic I meant to be
Oratie
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Acute and chronic pain after cardiac surgery
Promotores: C.A.J. Knibbe, D. Tibboel, Co-Promotor: P. Bruins
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Drug-target residence time: a case for the adenosine A1 and A2A receptors
Promotor: A.P.IJzerman, Co-Promotor: L.H. Heitman
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Dynamics of TNFalpha signaling and drug-related toxicity
In previous studies at our laboratory it was demonstrated that drug exposure of HepG2 cells can lead to an altered TNFα-induced NF-κB oscillatory phenotype, concurrent with a synergistically increased sensitivity for TNFα-induced apoptosis.
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Mechano-transduction mediated by integrin-based adhesion complexes: integration of cytoskeleton and adhesion dynamics
In this thesis, we focus on novel proteins/mechanisms that regulate integrin-adhesion mediated mechano-transduction.
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Lipid signaling and inflammation: metabolomics for better diagnosis and treatment strategy
Lipid signaling is an essential biological event/process in a plethora of pathophysiological conditions. The underlying idea of this thesis is that many of the roles and the complex interplay of the individual signaling lipids in inflammatory processes and related conditions in health and disease is…
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Profielwerkstuk
Hier vindt u links naar diverse pagina's die scholieren ondersteunen en stimuleren bij het maken van hun profielwerkstuk.
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Play by the rules? : coordination of EU sustainable development policies and the importance of the politico-legal context
There is an increasing amount of attention on EU and its Member States contributions to implementation of two landmark agreements: the Paris Climate Agreement and the UN Agenda 2030 with Sustainable Development Goals (SDGs). Absent from the current literature is an analysis of the political effect of…
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Integrating cellular and tissue dynamics with cell fate decisions through computational modeling
There is a need for alternative methods to replace, reduce and refine (3R) animal experimentation. Combining experimental data from high-throughput in vitro studies with in silico modeling is a promising approach to unravel the effect of chemicals on living cells and to gain a better understanding of…
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Macrophage activation and cholesterol in atherosclerosis development
Promotores:Th.J.C. van Berkel, M. van Eck
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The LeiCNS-PK3.0 model development and applications: healthy-to-diseased CNS pharmacokinetic translation
Accurate prediction of the unbound drug concentration-time profile at the CNS target site is crucial for the assessment of the right drug concentration-effect relationship. PBPK models have supported the PK prediction of the CNS target sites and the translation of PK data between species and between…
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Adjuvanted nanoparticulate seasonal influenza vaccines
Promotor: W. Jiskoot, Co-promotor: A. Kros
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The flux and flow of data: connecting large datasets with machine learning in a drug discovery envirionment
This thesis focuses on data found in the field of computational drug discovery. New insight can be obtained by applying machine learning in various ways and in a variety of domains. Two studies delved into the application of proteochemometrics (PCM), a machine learning technique that can be used to…
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Mechanistic modelling of drug target binding kinetics as determinant of the time course of drug action in vivo
Drug-target binding kinetics determine the time course of the central event in pharmacotherapy: Drug-target interaction.
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Multifunctional polypept(o)ide miktoarm star polymers for advanced drug delivery: from the development of versatile synthetic strategies for
With an emphasis on developing novel miktoarm star polymers termed PeptoMiktoStars, this thesis leverages asymmetric polymeric polypept(o)ide frameworks to advance their effectiveness in delivering hydrophobic drugs and nucleic acids.
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Mast cell-mediated immune modulation in experimental Rheumatoid Arthritis and Atherosclerosis
In this research project, we aimed to obtain more insight in the role of mast cells in the immune driven disorders rheumatoid arthritis and atherosclerosis.
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To affinity and beyond: novel molecular tools to explore solute carrier transport proteins
Despite being the second largest transmembrane protein family after GPCRs, the SLC superfamily has only gained significant attention in early drug development over the past decade.
