Promotor: Prof.dr. T.H.W. Bäck

The Standard Model (SM) of particle physics fails to explain several observed phenomena and is incomplete. In order to resolve this problem, one may extend the SM by adding new particles.

Promotor: M.K. Richardson, Co-Promotor: F. Witte

Traditional drug discovery approaches have been hampered by (in vitro) cell-culture models that poorly represent the situation in the human body.

Tracing the evolution of the molecular gas content in galaxies is critical for a complete understanding of galaxy formation and evolution, as it provides the direct fuel for star formation. Studies of high-redshift (z>1) molecular gas reservoirs, most commonly traced by carbon monoxide (CO), have seen…

Phosphorylation affects all four major biomolecules – proteins, lipids, carbohydrates and nucleic acids – and plays a pivotal role in the most fundamental cellular functions.

Promotor: Promotor: W.Th.F. den Hollander, Co-promotor: V. Sidoravicius.

Streptomyces are filamentous bacteria that produce more than two-thirds of known antibiotics.

The ability to count is a property not often attributed to materials, despite the abundance of memory in materials. Regardless of how a material stores information, it is often difficult to retrieve exactly ‘what’ a material remembers.

All crested and marbled newts (the genus Triturus) suffer from an unusual genetic abnormality, called a balanced lethal system, that kills exactly half of their offspring. How can a trait so disadvantageous have survived millions of years of natural selection?

Promotor: F. Arbab

This thesis applies data mining in commercial settings in the telecommunications industry.

Parkinson's disease is the second most common neurodegenerative disease in the world. One of its symptoms is the loss of dopaminergic neurons in the substantia nigra pars compacta.

Self-assembly is an abundant process in nature and is vital to many processes in living organisms.

Promotor: J.N. Kok, Co-promotor: C.M. Soares, A.J. Knobbe

The field of exoplanet research is rapidly advancing through the development of new technology, observing techniques, and post-processing methods.

Promotor: E. Gittenberger, Co-promotores: L.P. van Ofwegen; B.W. Hoeksema

Promotor: A. Kros

Marine sponges are important members of reef ecosystems, as they play ecological roles that are essential for the health of the reef.

The electrochemical oxygen reduction reaction (ORR) is an essential half-reaction for the utilization of hydrogen as a sustainable fuel, via the conversion of hydrogen to electrons and protons facilitated by the ORR. In the most common fuel cells, the ORR is requires high loadings of non-abundant platinum…

This thesis describes the development of improved formulations and alternative delivery strategies for polio vaccination.

Promotor: J. van der Greef, T. Hankemeier; Co-promotor: H.A. van Wietmarschen

Promotor: B.van de Water, Co-promotor: L.S.Price

In my research, I used a comparative wood anatomical approach to address wood evolution of the (largely) tropical flowering plant families Apocynaceae and Sapotaceae.

In this thesis, we have studied the potential of the zebrafish larval model in studying the ECS, as a complementary model to the existing rodent models.

A remarkable population of short period transiting rocky exoplanets with equilibrium temperatures on the order of 2,000 K has recently been discovered.

Promotores: Prof.dr. G.F.A Kersten, Prof dr. J.A. Bouwstra

Three major cosmology-focused missions are planned for the next decade: the Euclid space telescope, the Vera C. Rubin Observatory in Chile, and the Nancy Grace Roman Space Telescope.

Sepsis is a life-threatening condition caused by a dysregulated host response to infection, it is associated with significant morbidity, mortality, and with a high financial burden on global healthcare systems. Bacterial infections are the primary cause of sepsis, but the growing prevalence of antimicrobial…

Optical projection tomography (OPT) is a tomographic 3D imaging technique used for specimens in the millimetre scale.

In multi/many-core System-on-Chips (SoCs), the performance is almost linearly scaling with the number of processing elements.

This dissertation presents the results of the importance of creativity for ICT-students of Dutch universities of applied sciences (in Dutch: hogescholen), and the functioning of training courses that aim to promote creative abilities is highlighted.

Streptomyces present a valuable platform for natural product discovery. Lugdunomycin is a novel angucycline-derived polyketide from Streptomyces sp QL37, with unprecedented skeleton and antimicrobial activity.

The redox-conversion reaction of metal-disulfide and metal-thiolate complexes are important, as they may shed light on electron-transfer reactions that often occur in Nature.

An interdisciplinary collection of the best international scholarship on Muslim youth.

Thermodynamics is one of the founding scientific pillars that has helped us better understand heat engines, biology, ecosystems, and even black holes. While it fundamentally describes large systems by examining the bulk behavior of their constituents, it is anchored in the statistical equivalence of…

Studying the impact of urbanisation on the respiratory health of past Dutch populations (1200-1850 CE).

uman skin equivalents (HSEs) are in vitro 3D-skin models that mimic many aspects of the native human skin (NHS) and can be a valuable tool.

De Koninklijke Hollandsche Maatschappij der Wetenschappen (KHMW) heeft Leids natuurkunde-promovenda Anne Meeussen de Shell Afstudeerprijs voor Natuurkunde uitgereikt, met het bijbehorende prijzengeld van 5.000 euro.

Het collegeaanbod op het gebied van de kunsten (voornamelijk beeldende kunst en muziek) en van cultuur in de breedste zin.

Promotor: P.M. Brakefield

Van onderwijs tot een verrijkende ervaring

Koningin Máxima opende woensdag 4 september onder grote belangstelling het gerenoveerde tropische kassencomplex in de Hortus botanicus Leiden.

This thesis focuses on the application of lipid-based nanomedicine in drug delivery, including small molecular antitumor drugs and biomacromolecules including mRNA, and evaluates their biological performance.

The Leiden Institute of Advance Computer Science (LIACS) in collaboration with the Institute of Security and Global Affairs (ISGA) have developed the minor Cyber Security Governance Essentials to provide students with a mixture of technical and governance knowledge to set them on a path towards understanding…

Multicellular giant algae Chara species have been widely used in physiological studies for decades.

In de dreigingsmonitor bewaken en beveiligen 2022-2023 heeft het onderzoeksproject de dreigingsontwikkeling thematisch onderzocht.

Kom 16 december genieten van een uniek gratis concert. Met optredens van studenten van de Universiteit Leiden, die naast hun studie ook het talenttraject Practicum Musicae aan het Koninklijk Conservatorium in Den Haag volgen. Verschillende ensembles, kwartetten en duo’s en een gloednieuw orkest trakteren…

Lysosomal storage disorders (LSDs) are a group of orphan diseases characterized by lysosomal dysfunction or impaired lysosomal catabolism and affect collectively about 1 in 5000 live births.

Cardiovascular diseases are the primary cause of death in the world with atherosclerosis as primary underlying cause.