Business Process Model and Notation (BPMN) has become the standard for business processes diagrams.

Low-carbon (LE) technologies have a significant potential to reduce the total carbon emissions in China.

This thesis seeks to combine two different research topics; Multi-Objective Optimization and Complex Network Analysis.

Op 11 november 2021 verdedigde Evelien Campfens het proefschrift 'Cross-border Claims to Cultural Objects'. Het promotieonderzoek is begeleid door prof.dr. N.J. Schrijver en prof.dr. W.J. Veraart (VU Amsterdam).

Plants and their pollinators form complex interaction networks. Within these networks, species differ widely in the number of species they interact with.

Enzymes are innately sensitive to changes in the amino acid sequence, which largely constrains their evolutionary potential, i.e., evolvability. This evolutionary burden can be alleviated in the presence of stabilizing mutations, which increase the buffering capacity of enzymes to tolerate mutations…

Promotor: Prof.dr. S.F. Portegies Zwart

The focus of the described research in this thesis is on the oxidative stress response (Nrf2 pathway). The aim of the research presented in this thesis is to obtain more information concerning microRNAs which are involved in the Nrf2 pathway, to determine and evaluate the application of microRNAs for…

Promotor: A.P. IJzerman

A remarkable population of short period transiting rocky exoplanets with equilibrium temperatures on the order of 2,000 K has recently been discovered.

Promotores: Prof.dr. G.F.A Kersten, Prof dr. J.A. Bouwstra

Promotores: Prof.dr. B.R. Katzy, Prof.dr. K. Sailer (Munich University)

Promotor: G.F.A. Kersten, W. Jiskoot, Co-promotor: B. Metz

When observing star-forming galaxies, we are not only seeing stellar light, but we also see how this interacts with galactic gas and dust. This thesis contains studies of the stellar, nebular and dust properties of low mass star-forming galaxies.

Promotor: Prof.dr. S. Portegies Zwart

In this thesis integral points on affine del Pezzo surfaces are studied.

Biological cells, the basic building blocks of all life forms, are surrounded by a lipid membrane. More than half of the membrane is occupied by membrane proteins, which can regulate the cell functionality through specific arrangements.

The studies presented in the work show the potential of the integrative use of biophysical data in defining the structural basis of protein interactions.

Empirical Legal Studies in Leiden focuste op het bouwen van een interdisciplinaire gemeenschap van rechtsgeleerden en sociale wetenschappers die samen juridische vraagstukken onderzochten op het snijpunt van recht en gedrag, waarbij diverse soorten methoden werden gebruikt.

The growing demand of energy indicates that global energy resources in the form of fossil fuels will not be sufficient in the future. In order to solve potential future energy problems development of a sustainable hydrogen economy is highly desirable.

De onderzoeksgroep Organizational & Entrepreneurial Behavior onderzoekt het gedrag van individuen en groepen die in organisaties werken, organisaties starten, of organisaties leiden, met als doel om organisatorische praktijken te informeren. Door zich te concentreren op het gedrag van (groepen) werknemers,…

What are the pressing issues of our time, and how can different disciplines come together to address them? Studium Generale and Leiden University College (LUC) present the Global Challenges series: events that bring together researchers from LUC and experts from other disciplines to tackle a shared…

This joint Master with the Autonomous University of Barcelona will the equip you with the necessary competences to play a key role in the emerging field of transfusion medicine. The programme includes both transfusion of blood components and hematopoietic transplants, cellular and tissue therapy, and…

Goed werkgeverschap is net als goed werknemerschap een open norm. Daarmee is het onduidelijk en onzeker waar werkgevers zich op dienen te richten en welke rechten (en plichten) werknemers hebben in dat verband. De doelstelling van dit onderzoek is om invulling te geven aan de norm goed werkgeverschap…

This course explores international arbitration as one of the most common methods of international dispute settlement. You will gain an in-depth understanding of international arbitration through the analysis of its role as a mechanism of dispute settlement, its institutions, the fields of law it is…

This course explains the functions of each international court and tribunal in The Hague. On the basis of cases and interviews with judges and lawyers, this course explores the role of these courts and tribunals and their potential to contribute to global justice.

In this thesis an activity-based probe was discovered that could visualize the activity of PLAATs. With an optimized gel-based ABPP assay in hand, screening of a compound library led to the discovery of alpha-ketoamides as a hit for PLAAT3.

Hoewel er onder de elite en het publiek algemene consensus bestaat over de noodzaak van klimaatactie, is de bereidheid van het publiek om voor dergelijke inspanningen te betalen veel lager.

Promotor: A.P. IJzerman

Promotores: H.S. Overkleeft; G.A. van der Marel Co-Promotor: B.I. Florea

Promotor: A.P. IJzerman

Promotor: A.P. IJzerman Co-promotor: L.H. Heitman

As a virtually inexhaustible source, solar energy plays a major role in future global energy scenarios.

The soil ecosystem consists of the largest reservoir of biodiversity on Earth.

Cholesterol influences many pathways, including serving as precursor for adrenal steroidogenesis. Imbalance of cholesterol levels has been implicated in several diseases including cardiovascular diseases and its underlying pathology, atherosclerosis.

Mechanical metamaterials are man-made materials which derive their unusual properties from their structure rather than their composition.

In this research I assess the impact of the recently discovered gas reserves south off Cyprus on the escalation of the Cyprus conflict.

Promotores: Prof.dr. J. Schaye & Prof.dr. C. Steidel (California Institute of Technology)

M.T.M. Koper, Co-promotor: D.G.H. Hetterscheid

In this thesis, time-lapse fluorescent microscopy plays a pivotal role in investigating functional materials within living cells as well as the migratory behaviour of neural progenitor cells.

Multicellular giant algae Chara species have been widely used in physiological studies for decades.

Integrins play an essential role in multicellular life by connecting cells to the extracellular matrix.

Evolution acts via mutations in amino acid sequences. Substitution of essential amino acids leads to a nonfunctional protein. l.

Publicaties Onderwijs- en organisatieontwikkeling

Kunst en vrije tijd, Kunst en vrije tijd

This thesis aims to demonstrate how the achromatic nature and design flexibility of liquid-crystal optics can be used to improve high-contrast imaging instruments to facilitate detailed exoplanet characterization.

Climate change is a challenge for both current and future generations. New biological resources have to be developed in order to meet the demand for energy as well as the demand for food.

Promotor: Prof.dr. G.J. Kroes

Video games have emerged as one of the most interesting media of the turn of the century. The peculiar characteristic of video games is the biunivocal interaction between the computer and the human player.