Het Leiden Institute for Brain and Cognition (LIBC) houdt op 4 november het publiekssymposium ‘Onzekere tijden: struikelblok of springplank?’, dat de positieve kant van onzekerheid belicht. De bijeenkomst vindt plaats in de Stadsgehoorzaal in Leiden.

In this work we describe three methods to improve the performance of Quantum Field Theory calculations.

Het onderzoek van Anne Helder toont aan wat in het brein gebeurt als lezers een tekst lezen waarin iets staat dat niet klopt. Promotie 15 november.

Microglia support the central and peripheral nervous system by forming the first line of defense against hazardous events. Microglia are increasingly acknowledged as critical players in neurodegenerative diseases, highlighting them as potential therapeutic targets.

Promotor: A. Doelman, Co-promotor: J.D.M. Rademacher

Hoe kunnen mensen hun prestaties verbeteren en hun creatieve potentieel benutten? Dat is het onderwerp van het nieuwe Journal of Cognitive Enhancement. Dit interdisciplinaire wetenschappelijke tijdschrift is een initiatief van de Leidse psycholoog Lorenza Colzato. Eerste publicatie maart 2017.

Promotor: Prof.dr. C.U. Keller

An assessment approach that tailors to children’s instructional needs

Promotor: S.M. Verduyn Lunel, Co-Promotores: S.C.Hille, O.W. van Gaans

Het ProMiSe project heeft als doel om de ontwikkeling van kinderen met het Coffin-Siris syndroom en FOXP1 syndroom te onderzoeken. Deze kennis is belangrijk om ouders en zorgprofessionals beter te kunnen informeren en hen te ondersteunen bij de opvoeding.

Het onderzoek van de sectie Cognitieve Psychologie is onder te verdelen in twee domeinen.

Lorenza Colzato wil onderzoeken of het gebruik van probiotica en tryptofaan de sociaal-cognitieve achteruitgang die optreedt bij het ouder worden, kan vertragen. Daarvoor ontvangt Colzato samen met haar collega's in Duitsland en Spanje een JPI 'A Healthy Diet for A Healthy Life' Joint Transnational…

This study has been carried out in the community of Sukamiskin, a kelurahan (‘village’) in Bandung, the Capital of West Java Province, located in the Sunda Region of Indonesia.

When you have decided to participate in a Summer School of Leiden University, there are some matters you need to know before arrival. Please take a few minutes to read through the information here to find out what you can do from your side to smooth the process.

Promotor: Prof.dr. E. F. van Dishoeck

Vinasse is a major by-product generated by the sugarcane biofuel industry. It is a source of microbes, nutrients and organic matter and often it is recycled as fertilizer.

Phosphorylation affects all four major biomolecules – proteins, lipids, carbohydrates and nucleic acids – and plays a pivotal role in the most fundamental cellular functions.

Promotor: A.W. van der Vaart

Promotor: S.M. Verduyn Lunel, Co-promotor: O. van Gaans

Promotor: Prof.dr. T. Schmidt

Heart failure is a major health care problem with high mortality.

Cardiovascular syndromes are the major cause of death in Western societies.

Enzymes are innately sensitive to changes in the amino acid sequence, which largely constrains their evolutionary potential, i.e., evolvability. This evolutionary burden can be alleviated in the presence of stabilizing mutations, which increase the buffering capacity of enzymes to tolerate mutations…

Promotor: J.A. van Veen, Co-promotor: E.E. Kuramae

Promotor: J.P. Abrahams, Co-promotor: T. Grüne

This thesis discusses several questions regarding the double ramification cycle as a Chow class on the moduli space of stable n-pointed genus g curves using tools from so-called logarithmic geometry.

Promotor: Prof.dr. G.P. van Wezel

Promotor: Prof.dr. J.G.E.M. Fraaije, Co-promotor: A. Kros

Inflammatory skin diseases such as psoriasis and atopic dermatitis can severely impact both the physical and social aspect of a patient’s life. Aberrant inflammatory responses are thought to be a major causative factor in these disorders, but an abundance of different factors contribute to the development…

The studies presented in the work show the potential of the integrative use of biophysical data in defining the structural basis of protein interactions.

Promotor: H.P. Spaink, A.H. Meijer Co-promotor: R. Marin-Juez

This thesis seeks to combine two different research topics; Multi-Objective Optimization and Complex Network Analysis.

Optimization tasks in practice have multifaceted challenges as they are often black box, subject to multiple equality and inequality constraints and expensive to evaluate.

Promotores: Prof.dr. G.W. Canters, Prof.dr. T.J. Aartsma

Promotor: Prof.dr. J. den Hertog

The PID-directed shift in PIN polarity has been broadly accepted as one of the essential mechanisms for the regulation of auxin transport polarity.

Autophagy is a fundamental degradative process, maintaining cellular homeostasis and functions in host defense against intracellular pathogens, including mycobacteria and Salmonella.

Advanced UHF MRI techniques provide powerful tools for studying the zebrafish brain, an emerging model in neurological research. In this work, various MRI and localized MRS methods are optimized and employed for UHF strength for studying the zebrafish brain.

For each living organism health is ensured by correct functioning of its cells. Cells therefore have elaborate methods for regulation of their proteins.

Promotor: Prof.dr. W.Th.F. den Hollander, Co-promotor: R. Fernandez.

This dissertation focused on computational methods based on first principles calculations using the Density Functional Theory (DFT) framework. Emphasis was laid on affordable methods that can provide a tradeoff between computational expense and accuracy.

Binnen het brede netwerk van de Universiteit Leiden neemt het instituut deel aan onderzoek binnen de volgende profileringsgebieden:

This thesis covers various applications of topology in condensed matter physics and quantum information.

Leiden University’s Academic Challenge

Promotor: M.A.G.J. Orrit