A century ago, it was unclear whether the stars in the sky were clustered in groups, or widely spread in the universe.

Complex Organic Molecules (COMs) have been detected in objects across different stages of stellar evolution.

Promotor: Prof.dr. R.M.H. Merks

Promotor: A.P. IJzerman

Radiography is an important technique to inspect objects, with applications in airports and hospitals. X-ray imaging is also essential in industry, for instance in food safety checks for the presence of foreign objects.

Animal diet studies are critical for understanding ecological processes such as trophic interactions, energy flow, and nutrient cycling. By examining what animals consume, ecologists gain insights into species specialization, predator-prey relationships, and ecosystem management.

Promotor: Prof.dr. S. Portegies Zwart

This thesis explores how bees and hoverflies are distributed across the Dutch landscape and how ecological and landscape factors shape their occurrence.

Supervisor: P.J.J. Hooykaas Co-Supervisor: R. Offringa

In hoeverre biedt de eeuwigheidsclausule in de Duitse Grondwet een voldoende legitimatie voor democratische soevereiniteit?

De in Leiden afgestudeerde jurist Corinne Dettmeijer-Vermeulen was lange tijd de Nationaal Rapporteur Mensenhandel en Seksueel Geweld tegen Kinderen. Kom op 26 november luisteren naar haar Cleveringa-oratie.

Despite their ecological, cultural, and economic importance, lion (Panthera leo) populations in Kenya are declining rapidly due to retaliatory killings following livestock depredation, depletion of wild prey, habitat loss driven by human activities, climate change, and disease.

This thesis seeks to investigate how cancer-associated mutations affect the pharmacological properties of selected GPCRs—primarily A2AAR and 5-HT2CR—through a combination of ligand binding assays, signaling readouts, kinetic profiling, and cellular functional assays.

How do you engage society to stop biodiversity loss? How do you create political and social involvement to deal with climate change? And how do you balance the economic needs of industry with the negative effects of pollution? If you find these kinds of questions interesting, then this Pre-University…

In this dissertation, we work towards an experiment in which we aim to bring a micrometer sized magnet at the tip of a soft cantilever into a superposition.

In this thesis chemical and physical processes in the ice mantles on interstellar dust grains are studied.

Bacteria are highly complex and diverse organisms that have adapted to survive in ecological niches ranging from the most extreme to the most heterogeneous environments.

The aim of this thesis was to develop novel treatment strategies for different types of eye melanoma utilizing zebrafish models. We first establish orthotopic and ectopic xenograft models for uveal and conjunctival melanoma by engraftment of the immortalized cells derived from these tumors into zebrafish…

Promotor: M. Ubbink, Co-Promotor: R. T. Dame

We showed that constitutive and inducible chemical and morphological defenses against Western flower thrips differ between tomato and chrysanthemum plants.

Freshwater biodiversity has been threatened by eutrophication due to excessive nutrients in the environment. Releasing the freshwater species from such pressures requires efforts from industry and manufacturers to avoid emissions to vulnerable and high-risk regions.

Radio jets are important to the evoultion of galaxies. However, it is still not fully understood how a radio jet can be triggered.

Despite being the second largest transmembrane protein family after GPCRs, the SLC superfamily has only gained significant attention in early drug development over the past decade.

In the past decade many population studies have been performed with the Atacama Large Millimeter/submillimeter Array (ALMA) to understand the bulk properties of protoplanetary disks around young stars. These population studies mostly consisted of low mass stars, with relatively few of the disks around…

In this thesis, we have studied cell images from two types of cells, including pollen grains and the immune cells, neutrophils. These images are captured using a bright field microscope and a confocal microscope.

Detecting nanoscopic objects plays an important role in nanoscience in particular, in the rapidly growing field of nanobiology. The forebear to modern super-resolution microscopy for single molecule investigation, is fluorescence microscopy.

Promotor: B. van de Water, Co-promotor: E.H.J. Danen

The Low Frequency Array enables studies of low-frequency carbon radio recombination lines with unprecedented sensitivity, spectral and spatial resolution.

This thesis investigates the evolution and fate of gaseous exoplanets, which are continuously shaped by stellar activity across both short and long timescales.

This thesis aims to test in vitro pipelines to rapidly and cost-effectively identify molecular mechanisms that drive adverse outcomes in clinical use.

Aan de vooravond van de Tweede Wereldoorlog kende Leiden de grootste Indonesische studentengemeenschap van Nederland. Veel van deze studenten belandden in het verzet tegen de Duitse bezetter. Daarna vochten sommigen van hen voor een onafhankelijk Indonesië.

The global agri-food system plays a critical role in food security and environmental issues.

S.S. Kolipaka’s thesis questions and investigates the survival prospects of reintroduced tigers and their offspring’s in the human dominated landscape of Panna tiger reserve in India.

Promotor: Peter Stevenhagen

Promotores: H.S. Overkleeft, G.A. van der Marel, Co-Promotor: R.G. Boot

On a structural level, the properties featured by a majority of mechanical metamaterials can be ascribed to the finite number of soft internal degrees-of freedom allowing for low-energy deformations.

Breeding for resistance becomes more and more important because we want to reduce the use of pesticides. A fast and cheap alternative can be to make use of morphological or chemical markers.

This thesis systematically studies the physicochemical properties of non-planar, propeller-shaped, polycyclic aromatic hydrocarbons. The synthesis of several so-called propellerenes is described on a gram scale, using optimized procedures aimed at using less hazardous reagents and reducing the amount…

Bacteria often experience external challenges, such as changes in environmental conditions or attacks by bacteriophages.

Promotores: J. Kok, M. Chaudron (Chalmers University)

In this research I assess the impact of the recently discovered gas reserves south off Cyprus on the escalation of the Cyprus conflict.

Metastasis is responsible for over 90% of cancer-related deaths and arises from the ability of a small subset of tumor cells to detach from the primary tumor, overcome multiple biochemical and mechanical barriers, disseminate through the body, and colonize distant organs.

Op 4 mei herdacht de Universiteit Leiden de slachtoffers van de Tweede Wereldoorlog uit onze universitaire gemeenschap. Alumni, (oud)medewerkers van de universiteit en studenten kwamen bijeen voor dit Uur van Herinnering.

De Duitse historicus Katja Happe is de nieuwe Cleveringahoogleraar van de Universiteit Leiden. Ze houdt op 26 november 2019 de Cleveringa-oratie. Happe doet onderzoek naar de Jodenvervolging in Nederland en schreef daarover het alom geprezen boek ‘Veel valse hoop’.

De jaarlijkse dodenherdenkingen op de Dam en Waalsdorpervlakte, de Nederlandse excuses voor het slavernijverleden en de Cleveringa-oratie zelf: onze omgang met de geschiedenis is vaak vooral ritueel, vertelt Cleveringahoogleraar Frank van Vree die op 27 november zijn oratie uitspreekt.

Lees hier alles over de geschiedenis van de Universiteit Leiden, de oudste universiteit van Nederland. De Academia Lugduna Batava werd opgericht in 1575 en heeft als motto: Libertatis Praesidium ('Bolwerk van vrijheid').

China is een belangrijke partner voor de Universiteit Leiden. We werken samen met meer dan 20 Chinese universiteiten en in Leiden studeren zo'n 500 Chinese bachelor-, master- en PhD-studenten. Leiden heeft China aangewezen als prioriteitsland waarmee het een partnerprogramma voor langetermijnsamenwerking…

Leidse expertise op het gebied van China is van groot belang voor de veiligheid, welvaart en strategische positie van Nederland. China speelt een centrale rol in mondiale politieke verhoudingen, internationale handel, technologie en veiligheidsvraagstukken.

Kijk regelmatig op deze pagina voor meer informatie over het vergroten van de biodiversiteit aan de Universiteit Leiden.