2,385 zoekresultaten voor “working from hoe” in de Publieke website
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The evolution and plasticity of life histories upon variation in nutrition: on aging focused integrative approach
Promotores: Prof.dr. P.M. Brakefield, Prof.dr. B.J. Zwaan (Wageningen Universiteit)
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Metabolomics approaches for unravelling host-gut microbiota changes in different stages of cognitive impairment
The investigation into the bidirectional communication between the gut and its host is a rapidly growing area of research, attracting considerable attention for its potential to provide crucial insights into health and disease.
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Genetic diversity in the lion (Panthera leo (Linnaeus 1758)): unravelling the past and prospects for the future
Promotor: Prof.dr. G.R. de Snoo
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Gibbs-non-Gibbs transitions and vector-valued integration
Promotor: W. T. F. den Hollander, F. H. J. Redig
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Pharmacogenomics in drug development: implementation and application of PKPD model based approaches
Promotor: Prof.dr. M. Danhof, Co-Promotor: J. de Jongh
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Exploring the Edge
At the largest scales, two ingredients dictate the distribution of matter in the Universe. The first is dark matter, acting as an invisible scaffolding held together by gravitational forces.
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Meta-heuristics for vehicle routing and inventory routing problems
Promotores: T.H.W. Bäck, Y. Tan, Co-promotor: M.T.M. Emmerich
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Graphene at fluidic interfaces
In this thesis unconventional tools based on fluidic interfaces were developed to study the surface and interfacial chemistry of graphene, to characterize the intrinsic properties of graphene, to disentangle the effects of substrate and of the environmental factors, and to improve handling protocols…
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Fate, accumulation and impact of metallic nanomaterials in the terrestrial environment
The rapidly increasing commercial application of metallic nanoparticles within products will inevitably enhance the amount of NPs being released into soil.
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Stereoelectronic and conformational effects in oxocarbenium, iminium and iminosugar ammonium ions
Promotores: Prof.dr. G.A. van der Marel, M. van Heel
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The role of the Arabidopsis AHL15/REJUVENATOR gene in developmental phase transitions
This thesis describes the functional analysis of the Arabidopsis AHL15 gene.
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Atmospheres of hot alien Worlds
Promotor: Prof.dr. I.A.G. Snellen, C.U. Keller
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Quantification in untargeted mass spectrometry-based metabolomics
Promotor: T. Hankemeier, Co-promotor: T.H. Reijmers
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Unraveling modular architecture and domain engineering of carbohydrate-active enzymes: key insights for sustainable bio-based processes
This thesis examines enzyme domain architecture and engineering to improve the breakdown of lignocellulose and starch, abundant biopolymers crucial for sustainable biofuel and biochemical production. Carbohydrate-active enzymes (CAZymes) facilitate this degradation, but the structural complexity of…
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Impact of low-carbon electricity development on carbon emissions in China
Low-carbon (LE) technologies have a significant potential to reduce the total carbon emissions in China.
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Morphodynamic equilibria in tidal inlet systems: sensitivity to geometrical variations
A tidal basin is an inland sea which is almost entirely enclosed by land and connected to the open sea by a tidal inlet. Through the tidal inlets interaction takes place between the tidal basin and the open sea.
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Two-Prover Bit-Commitments: Classical, Quantum and Non-Signaling
This thesis considers multi-prover commitment schemes whose security is based on restrictions on the communication between the provers.
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Reverse engineering of drug induced QT(c) interval prolongation: Towards a systems pharmacology approach
Promotor: M. Danhof Co-promotor: O.E. Della Pasqua
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Unravelling cell fate decisions through single cell methods and mathematical models
Despite being the object of intense study, embryonic development has been difficult to model due to a number of reasons. First, complex tissues can be comprised of many cell types, of which we probably only know a subset.
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Stochastic resetting and hierarchical synchronisation
Stochastic resetting is simple enough to be approached analytically, yet modifies stochastic processes in a non-trivial way.
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Steady-State Analysis of Large Scale Systems
Promotor: W.Th.F. den Hollander Co-Promotor: F.M. Spieksma
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Neutral outflows in high-redshift dusty galaxies
Outflows are crucially important for the gas budget and evolution of luminous star-forming galaxies and AGNs, with observed mass outflow rates of the same order as the star formation rate. Greater star formation and black hole growth lead to more intense feedback and outflows, resulting in self-regulated…
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Figuring rural development: concepts and cases of land use, sustainability and integrative indicators
Promotores: Prof. dr. G.R. (Geert) de Snoo, Dr. E. (Ester) van der Voet
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Triblock polypept(o)ides for siRNA delivery: unique polymeric designs for versatile carrier systems
Utilizing the polymeric platform of polypept(o)ides, this thesis describes synthesis and investigation of novel triblock copolymers to obtain carrier systems with multiple compartments for efficient siRNA delivery. Although the individual microstructure of nanoparticles differs depending on the polymeric…
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Omics data integration with genome-scale modelling of dopaminergic neuronal metabolism
Parkinson's disease is the second most common neurodegenerative disease in the world. One of its symptoms is the loss of dopaminergic neurons in the substantia nigra pars compacta.
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Balsaminaceae in Southeast Asia: systematics, evolution, and pollination biology
Balsaminaceae is a diverse plant family characterized by a huge floral morphological diversity.
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Musems, Collections and Society | Yearbook 2021
In this Yearbook you will find some fascinating examples of what was done in 2021, not only by ourselves, but also by our international colleagues.
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Lights in a sea of darkness: constraining the nature and properties of dark matter using the stellar kinematics in the centres of ultra-faint
Dark matter is one of the biggest mysteries of the Universe. Its properties cannot be explained with the known laws of physics and elementary particles.
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Lines in the sand: behaviour of self-organised vegetation patterns in dryland ecosystems
Vast, often populated, areas in dryland ecosystems face the dangers of desertification.
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Invariant manifolds and applications for functional differential equations of mixed type
Promotor: S.M. Verduyn Lunel
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Smoothly breaking unitarity : studying spontaneous collapse using two entangled, tuneable, coherent amplifiers
The Copenhagen interpretation of quantum mechanics states that a measurement collapses a wavefunction onto an eigenstate of the corresponding measurement operator.
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Multiple star formation: chemistry, physics and coevality
Multiple stars, that is two or more stars composing a gravitationally bound system, are common in the universe.
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Algorithm design for mixed-integer black-box optimization problems with uncertainty
The increasing competition in the automotive industry requires the tailored, swift development of technologically sophisticated vehicles. Therefore, the computationally expensive state-of-the-art simulation technologies are combined with optimization algorithms. An example of a real-world optimization…
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Histone-DNA assemblies in archaea. Shaping the genome on the edge of life
All life on earth contains DNA, which is used to store biological information. Organisms compact their DNA in order for it to fit inside their cell(s).
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Pattern mining for label ranking
Promotor: J.N. Kok, Co-promotor: C.M. Soares, A.J. Knobbe
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Laborinth II : denken als experiment : 472 'meditaties' over de noodzaak van het creatief denken en experimenteren in het uitvoeren van complexe
Dit proefschrift onderzoekt de noodzaak van het creatief denken en experimenteren in het uitvoeren van complexe muziek in de late twintigste- en vroege eenentwintigste eeuw.
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Structural Health Monitoring Meets Data Mining
Promotor: Prof.dr. J.N. Kok, Co-promotor: A.J. Knobbe
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Evolvability and epistasis studied through the lens of an antibiotic resistance enzyme
Enzymes are innately sensitive to changes in the amino acid sequence, which largely constrains their evolutionary potential, i.e., evolvability. This evolutionary burden can be alleviated in the presence of stabilizing mutations, which increase the buffering capacity of enzymes to tolerate mutations…
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Understanding protein complex formation: The role of charge distribution in the encounter complex
Protein–protein complexes are formed via transient states called encounter complexes that greatly influence the formation of the stereospecific complex.
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Filter-based reconstruction methods for tomography
Promotor: K.J. Batenburg
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Improved hard real-time scheduling and transformations for embedded Streaming Applications
This thesis addresses the problem of designing performance and energy efficient embedded streaming systems, that is, systems which process a stream of input data coming from the environment and generate a stream of output data going into the environment.
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Deepening the uncertainty dimension of environmental Life Cycle Assessment: addressing choice, future and interpretation uncertainties.
LCA has become an important method to study environmental impacts of human activities. Still, there are several methodological issues in LCA that can adversely affect the results reliability.
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Logarithmic approach to the double ramification cycle
This thesis discusses several questions regarding the double ramification cycle as a Chow class on the moduli space of stable n-pointed genus g curves using tools from so-called logarithmic geometry.
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Breeding birds on organic and conventional arable farms
Promotor: G.R. de Snoo
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Development of personalized health monitoring using ultra-weak photon emission based on systems medicine concepts
Promotor: Jan van der Greef; Co-promotors: Mei Wang; Eduard van Wijk
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Laboratory studies of Water Ice in Space
Astronomical observations of cold regions in the universe show a rich inventory of ices. Part of these ices may end up on planets like our own, but in that journey they will be exposed to considerable amounts of radiation.
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Mass Spectrometry-Based Degradomics Analysis of Toxoid Vaccines
The chemical and structural heterogeneity of toxoid vaccines makes their analysis challenging. However, detailed insights on a molecular level can be obtained by mass spectrometry.
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Chaotic dynamics in N-body systems
Promotor: Prof.dr. S.F. Portegies Zwart
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Design, implementation and evaluation of transnational collaborative programmes in astronomy education and public outreach
Promotores: Prof.dr. G. Miley & Prof.dr. J.M. van den Broek
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Visual Revolutions in the Middle East
Special Issue in: Visual Anthropology, Volume 29, Issue 3, 2016
