Onderzoeksgroepen in het Quantum Matter & Optics onderzoeksprogramma onderzoeken elektronische eigenschappen van interacties van materie en lichtmaterie, met de nadruk op quantuminformatie.

As a virtually inexhaustible source, solar energy plays a major role in future global energy scenarios.

Promotor: K.E. Schalm, Co-promotor: S.S. Lee

Inverse problems are problems where we want to estimate the values of certain parameters of a system given observations of the system. Such problems occur in several areas of science and engineering. Inverse problems are often ill-posed, which means that the observations of the system do not uniquely…

Promotor: H.J.M. de Groot

Protein–protein complexes are formed via transient states called encounter complexes that greatly influence the formation of the stereospecific complex.

Promotor: Prof.dr. M. Ubbink

We find ourselves in an era of transition, not just towards a more computing- and data-driven society but also away from unsustainable fossil fuels as an energy source.

Promotor: R. Gill, Co-promotor: P. Massart

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Promotie

Hydrogen peroxide (H2O2) is an important bulk chemical that is used in various industrial processes. More than 95% of the H2O2 used in industry is made via the anthraquinone process during which a large amount of energy is going to waste.

Cryogenic electron microscopy (cryo-EM) is a powerful technique used to visualize the inside of cells and to study specific protein complexes. Within this thesis, I describe the use of various cryo-EM techniques to gain insight into the structural changes of the human pathogen, Vibrio cholerae, as it…

Promotor: T.J. Aartsma, Co-promotor: R.N. Frese

Promotores: Prof.dr. H.J.M. de Groot, Prof.dr. J. Matysik (Universitaet Leipzig)

Despite the fact that gold nanoparticles (GNPs) are one of the most studied nanoparticles, there is still a necessity for new approaches allowing for effective protective coating to enable wider use of GNPs in biomedical applications.

Kunstmatige fotosynthese heeft als doel om via chemische processen zonne-energie om te zettn in brandstof. Semi-kunstmatige fotosynthese is een hybride aanpak waarbij chemische maar ook biotechnologische processen worden gebruikt. Wij hebben als doel om een hybride systeem te ontwikkelen met behulp…

Een bacterie supersnel bevriezen, om de structuur van buiten en binnen natuurgetrouw in beeld te brengen. Hoogleraar Ultrastructuurbiologie Ariane Briegel kwam speciaal hiervoor naar Leiden: de Universiteit Leiden is een van de weinige instituten wereldwijd waar de benodigde apparatuur beschikbaar is.…

This thesis develops a method for direction dependent calibration of the ionosphere in radio interferometric data.

This thesis focuses on amyloid proteins, a class of proteins that convert into amyloid fibrils.

This thesis covers various applications of topology in condensed matter physics and quantum information.

Het blad Science publiceert drie artikelen tegelijk over een belangrijke ontdekking in vastestoffysica. Leids natuurkundige Jan Zaanen bespreekt deze ontdekking in dezelfde uitgave van 4 maart.

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Met elektronspins hebben natuurkundigen het bindingsproces onderzocht van het eiwit α-synucleïne, dat wordt geassocieerd met de ziekte van Parkinson. Wat blijkt is dat het eiwit op een verrassend efficiënte manier bindt aan een hersenmembraan. Met deze in Leiden ontwikkelde methode hebben de onderzoekers…

Een speciaal type microscoop jaagt momenteel een revolutie aan in de biologie: de cryo-elektronenmicroscoop. Twee van zulke giganten staan sinds 2011 op de Leidse Faculteit der Wiskunde en Natuurwetenschappen. Hoogleraar Ultrastructuurbiologie Ariane Briegel vertelt hierover in het NRC Handelsblad.

This thesis presents the results of a study on the interfaces of insulating oxides with and without the insertion of a magnetic layer.

Many galaxy clusters exhibit bright diffuse radio emission that traces the underlying structure of the intracluster medium (ICM).

Promotor: Prof.dr. C.W.J. Beenakker

Promotor: T.H. Oosterkamp

Geometric phases lead to a nontrivial interference result when an electron's different quantum mechanical paths choices encircle a magnetic coil in an Aharonov-Bohm experiment.

Advanced sensing techniques require graphene with high quality and well-controlled surface chemistry.

Majorana fermions in superconductors are the subgap quasiparticle excitations that are their own antiparticles.

The elementary excitations of magnets are called spin waves, and their corresponding quasi-particles are known as magnons. The rapidly growing field of Magnonics aims at using them as information carriers in a new generation of electronic devices, (almost) free of electric currents.

Hydrodesulfurization (HDS) is an ubiquitous part of oil refining that ensures that fuels are cleaned of impurities and environment release of pollutants such as SOx and NOx gasses are minimized.

The electrochemical oxygen reduction reaction (ORR) is an essential half-reaction for the utilization of hydrogen as a sustainable fuel, via the conversion of hydrogen to electrons and protons facilitated by the ORR. In the most common fuel cells, the ORR is requires high loadings of non-abundant platinum…

In my research, I used a comparative wood anatomical approach to address wood evolution of the (largely) tropical flowering plant families Apocynaceae and Sapotaceae.

Promotor: R. Tijdeman, Co-promotor: H.J.J. te Riele

Promotor: J. Aarts

Bacteriophages, or phages for short, are the most abundant biological entity in nature. They shape bacterial communities and are a major driving force in bacterial evolution.

What physics controls the properties of quantum matter, such as how electrons flow inside high-temperature superconductors? This question has captivated the physics community and industry for decades, in part due to the great technological potential such materials have, but also because they have resisted…

Traditional biochemical methods for studying organelles require cell disruption, preventing the real-time observation of dynamic intracellular processes.

Het logo van de Universiteit Leiden, met letters zo klein als een bacterie. Wetenschappers van het LUMC en het Instituut Biologie hebben het kleinste logo ooit van onze universiteit gemaakt. Een grapje met een serieuze ondertoon: met de nieuwe microscoop waarmee het logo is gemaakt, kunnen zij nog gedetailleerder…

A single self-assembled semiconductor quantum dot in a high-finesse optical microcavity - the subject of this thesis - is an interesting quantum-mechanical system for future quantum applications. For instance, this system allows trapping of an extra electron and thus can serve as a spin quantum memory,…

Synthetic hydrogels that mimic the natural extracellular matrix in the biophysical and biochemical cues it provides to cells are in high demand, however the cell phenotypes as they are observed in vivo in numerous cases have yet to be attained.

A difficulty of studies on chemical kinetics are the reaction time scales and detection of their intermediates.

This thesis systematically studies the physicochemical properties of non-planar, propeller-shaped, polycyclic aromatic hydrocarbons. The synthesis of several so-called propellerenes is described on a gram scale, using optimized procedures aimed at using less hazardous reagents and reducing the amount…

Large parts of the research described in this Thesis aims at the development of oligopeptide-masked toxins and their in situ immunoproteasome-mediated activation.

Promotor: Prof.dr. E. Bouwman, Co-promotor: S. Bonnet