3,251 zoekresultaten voor “alamsi in the spotlight” in de Publieke website
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Bound for Devotion: The Prayer Book as Object and Practice, 1300–1800
Congres/symposium
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Beyond Post-Communism: Imagining the Future in Times of Transition
Hoe stelden mensen in Centraal- en Oost-Europa zich de toekomst voor tijdens de overgangen van de jaren 1980 en 1990? De overkoepelende term 'postcommunisme' geeft geen antwoord op deze vraag. Dit project onderzoekt hoe schrijvers en cultuurtheoretici de potentiële toekomst van hun samenlevingen zagen…
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Mechanistic modelling of drug target binding kinetics as determinant of the time course of drug action in vivo
Drug-target binding kinetics determine the time course of the central event in pharmacotherapy: Drug-target interaction.
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developments in automated structure solution and crystallographic studies of the Sso10a2 and human C1 inhibitor protein
Promotor: Prof.dr. J.P. Abrahams, Co-Promotor: N.S. Pannu
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Beyond Dissemination: Hindustani Identifications at the Nexus of Tradition and Modernity
Een interdisciplinaire culturele analyse van de manier waarop de Hindoestaanse dubbele migratie hedendaagse identificatieprocessen beïnvloedt en de juxtapositie van traditie en moderniteit problematiseert.
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Advancing image-based localization of lipid-based nanomedicines for the exploration of targeted drug delivery
Microscopic insight on lipid-based nanomedicine in vivo remains limited to the perception of the knowledge that could be obtained: if we interpret only what we see, then we only believe to know. Although believing to know encapsulates an undefined amount of uncertainty in the exploration of lipid-based…
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To explore the drug space smarter: Artificial intelligence in drug design for G protein-coupled receptors
Over several decades, a variety of computational methods for drug discovery have been proposed and applied in practice. With the accumulation of data and the development of machine learning methods, computational drug design methods have gradually shifted to a new paradigm, i.e. deep learning methods…
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Development and application of cryo-EM tools to study the ultrastructure of microbes in changing environments
Cryogenic electron microscopy (cryo-EM) is a powerful technique used to visualize the inside of cells and to study specific protein complexes. Within this thesis, I describe the use of various cryo-EM techniques to gain insight into the structural changes of the human pathogen, Vibrio cholerae, as it…
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Leids Universitair Medisch Centrum
Het LUMC staat voor de verbetering van de gezondheidszorg en de gezondheid van mensen. Deze missie brengen de medewerkers van het LUMC dagelijks in de praktijk met toonaangevend onderzoek, vernieuwend onderwijs en optimale, innovatieve zorg.
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Determining the most appropriate dose metrics for evaluating dose-response relationships of metal-based nanoparticles to Zebrafish embryos
Promotores: Prof.dr. W.J.G.M. Peijnenburg & Dr. M.G. Vijver
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Disentangling a complex genus: systematics, biogeography and bioactivity of the genus Phyllanthus L. and related genera of tribe Phyllantheae (Phyllanthaceae)
The largest genus within the Phyllanthaceae family is a group called Phyllanthus L. Recent studies have shown, that Phyllanthus is paraphyletic with the genera Glochidion, Breynia and Synostemon nested within it.
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Modelling the role of mycorrhizal associations in soil carbon cycling: insights from global analyses of mycorrhizal vegetation
In this PhD study, I aim to deepen our understanding of the influence of major mycorrhizal types, namely arbuscular mycorrhizae (AM) and ectomycorrhizae (EM), on the global soil carbon cycle and their potential distribution changes under future environmental shifts.
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Designing 'context-specific' regional innovation policy: a study on the role of regional government in six European regions
Whilst government’s ability to design ‘context-specific’ regional innovation policy is generally assumed to depend on the region’s decision-making power, the aim of this study is to investigate how regional government matters. In order to open up the black box of policy design, the study develops a…
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MAPHSA - Mapping the Archaeological Pre-Columbian Heritage in South America
Het archeologisch erfgoed van Zuid-Amerika wordt in toenemende mate bedreigd door de uitbreiding van landbouwactiviteiten, de uitbreiding van infrastructuur, illegale houtkap en de huidige bosbranden die het Amazonegebied en andere gebieden van het continent teisteren.
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Migrants in between. The construction of illegal and temporal migration, 1945-2000
Deelproject van
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Brand new translation, same old story: the perpetuation of female and racial stereotypes in (re)translation
Promotie
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The impact of non-genetic factors on drug metabolism: towards better phenotype predictions
This thesis investigates how non-genetic factors, such as inflammation and concomitant medication, impact hepatic drug metabolism and subsequent drug metabolizing phenotype predictions.
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The development of molecular tools for investigating NAD+ metabolism and signalling
Nicotinamide adenine dinucleotide (NAD+) is the substrate used for the introduction of the ubiquitous and highly dynamic PTM in which either one or multiple adenosine diphosphate ribose (ADPr) moieties are covalently attached to a nucleophilic side chain of an specific amino acid in the target protein…
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Novel role of the AT-HOOK MOTIF NUCLEAR LOCALIZED 15 gene in Arabidopsis meristem activity and longevity
Plant architecture has distinct forms in different plant species, but also within a species the finalarchitecture of a plant is determined by its gradual development and changes therein induced by environmental conditions during the plant’s life cycle.
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Paving the path between low- and high-mass star formation: dynamics probed by Herschel far-infrared spectroscopy
Promotor: Prof.dr. E.F. van Dishoeck, Prof.dr. F.F.S. van der Tak (RUG)
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Rice Eaters in the Land of Cheese
Promotie
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Unraveling the surface formation of regular and deuterated water in space: a combined laboratory and computational study
Promotor: Prof.dr. H.V.J. Linnartz
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Fantastic: Nano- and microplastics and their impact on terrestrial plants and the food chain
Plastics have become an integral part of modern society due to their versatility and durability.
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Measuring sustainability: an elaboration and application of the system of environmental-economic accounting for Indonesia
Indonesia is experiencing various environmental challenges related to its fast economic growth. Therefore, it is necessary to have measurable and applicable indicators to obtain accurate data and information regarding the costs of adverse environmental impacts arising from economic activities to support…
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The flux and flow of data: connecting large datasets with machine learning in a drug discovery envirionment
This thesis focuses on data found in the field of computational drug discovery. New insight can be obtained by applying machine learning in various ways and in a variety of domains. Two studies delved into the application of proteochemometrics (PCM), a machine learning technique that can be used to…
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The trials and tribulations of PAHs in asteroids: investigating aqueous alteration of polycyclic aromatic hydrocarbons under asteroidal conditions
Carbonaceous asteroids preserve a record of early solar system processes, where minerals and organic molecules, like polycyclic aromatic hydrocarbons (PAHs), offer clues to planetary evolution and prebiotic chemistry.
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Functional characterization and unraveling the Gene Regulatory Networks (GRNs) of HD-Zip transcription factor HB40 (and HB22) in Arabidopsis
In this Ph.D. thesis, we characterized two novel upstream regulators of JUB1, HB40, and HB22, in Arabidopsis thaliana. In Chapter 2, we described functions of HB40 in modulating growth and development via the regulation of JUB1 and GA inactivation genes GA2OXs.
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Transdisciplinary Perspectives on Validity: Bridging the Gap Between Design and Implementation for Technology-Enhanced Learning Systems
Technologies that help to enhance our educational environments can be found everywhere.
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Motherhood and Unfreedom in the Islamicate World
Congres/symposium
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Assessing the link between television consumption and the attitudes toward people living with HIV/AIDS in Chile
We analyse the link between media consumption and the attitudes toward people living with HIV/AIDS in Chile. We used data from a sample of 1000 people, obtained in the 2011 wave of the World Values Survey (WVS). We use a logistic binary regression model by maximum likelihood. Our results suggest that…
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Stuck on the stairway of change: the EU’s enlargement and security and defence policies post 2022
In dit artikel presenteren Dimitrova, Gürkan en Koops een algemeen kader voor het vastleggen en systematisch analyseren van kritieke momenten en gradaties van verandering in EU-beleid.
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The EU’s Conceptualisation of the Rule of Law in its External Relations: Case Studies on Development Cooperation and Enlargement
Op 26 juni 2019 verdedigde Lisa Louwerse haar proefschrift 'The EU’s Conceptualisation of the Rule of Law in its External Relations: Case Studies on Development Cooperation and Enlargement'. Het promotieonderzoek is begeleid door promotor prof. mr. C.A.P. Hillion.
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Unlock the cyber crisis: Developing the prototype of an escape room-style cooperative game for cybersecurity education
Het project beoogt een escape room-achtig spel te ontwikkelen om studenten cybercrisismanagement te leren en voor te bereiden op uitdagingen in cybersecurity.
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Chinese assertiveness and the rise of Xi Jinping: ideational mobilization, elite contestation, and the struggle over regional order
In 2009-2010 ontstond in het westerse discours het idee van een meer ‘assertief’ China, een opvatting die China krachtig van de hand wijst. Niettemin is, vooral sinds Xi Jinping in 2012 aan de macht kwam, duidelijk dat China zijn lang gehanteerde buitenlandse beleidsdoctrine van ‘een lage profilering…
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The Grotius Sanction: Deus Ex Machina. The legal, ethical, and strategic use of drones in transnational armed conflict and counterterrorism
Op 21 maart 2019 verdedigde James Welch zijn proefschrift 'The Grotius Sanction: Deus Ex Machina. The legal, ethical, and strategic use of drones in transnational armed conflict and counterterrorism'. Het promotieonderzoek is begeleid door promotor prof. dr. P.B Cliteur.
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Leiden University College
Wat is mijn bijdrage aan onze wereld? Dat is de vraag die studenten en onderzoekers van het Leiden University College The Hague (LUC) zichzelf dagelijks stellen. Ze willen in hun onderwijs en onderzoek stappen vooruitzetten op het gebied van de vier global challenges ‘Peace and justice’, ‘Sustainability’,…
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Instituut Bestuurskunde
Het Instituut Bestuurskunde werkt aan complexe problemen waar de publieke sector in de 21ste eeuw mee te maken heeft: van klimaatbeleid tot de gevolgen van de digitalisering. De onderzoekers van het Instituut Bestuurskunde analyseren, duiden en denken mee over oplossingen voor de maatschappelijke uitdagingen…
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Andrew Gawthorpe in several media: 'Trump is less constrained than ever before'
Lecturer Andrew Gawthorpe of Leiden University discusses in The Conversation the growing influence of far-right activist Laura Loomer in Donald Trump’s administration.
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LUC The Hague Topopleiding 2016
Leiden University College The Hague is één van de beste university colleges van Nederland. Dat blijkt uit de jaarlijkse ranglijst in de Keuzegids Universiteiten 2016.
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Leiden University College The Hague (LUC) is het internationale honours college van de Universiteit Leiden.
Leiden University College The Hague (LUC) is het internationale honours college van de Universiteit Leiden. Het LUC The Hague biedt gemotiveerde en getalenteerde studenten van over de hele wereld een innovatieve Liberal Arts & Sciences bacheloropleiding.
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Bereid je voor op je studie
Ontdek hoe je je kunt voorbereiden op de masteropleiding The Politics of Artificial Intelligence aan de Universiteit Leiden: oriëntatieactiviteiten, academische bronnen, visumadvies en studentenondersteunende diensten.
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Boekpresentatie "Marginalized Religion and the Law in the Roman Empire"
Lezing
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Opening POPCorner The Hague
Met een openingswoord, een paneldiscussie op de Spaanse Trappen in Wijnhaven en een druk op de rode knop voor het gebouw zelf, is POPcorner The Hague donderdagmiddag officieel geopend door rector magnificus Hester Bijl.
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"The First Stars" & "Uncovering the oldest stars in the Milky Way"
Lezing, Astronomy on Tap
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The mind in the courtroom
Promotie
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Afforesting with microbes: disentangling the effect of soil biotic and abiotic characteristics on trees using soil inoculation
In this thesis I examine how soil biotic and abiotic characteristics change and interact throughout the course of afforestation and how they subsequently impact tree performance.
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Leidse Impact
Bezuinigen en beboeten: dat is wat het nieuwe kabinet voorstelt. Dat het desastreuze gevolgen gaat hebben vereist geen academisch onderzoek. Het belang van ons onderzoek, en de essentiele bijdragen die Leiden al eeuwen levert aan de Nederlandse samenleving verdienen een spotlight in de politieke waan…
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On a quest to discover where stellar-mass black holes merge: testing the AGN binary formation channel with spatial correlation analyses
The physical origin of the dozens of stellar-mass binaries, the mergers of which have been detected by the LIGO-Virgo-KAGRA collaboration via gravitational waves, is still unknown.
- Masterclass: Religious Imagination in the Late Medieval Low Countries
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Unmasking the Term 'Dual Use' in EU Spyware Export Control
Dit artikel illustreert hoe de term 'dual use' geassocieerd is geraakt met een bredere dichotomie tussen 'legitieme' en 'illegale' doeleinden.
