Interactive exploration of large volumes of data is increasingly common, as data scientists attempt to extract interesting information from large opaque data sets. This scenario presents a difficult challenge for traditional database systems, as (1) nothing is known about the query workload in advance,…

In condensed matter systems electron-electron interactions, negligible in everyday metals, can dramatically alter the electronic behavior of the system. Examples of such altered behavior include high-temperature superconductivity and modulation of the electron density.

The following report discusses a survey on the topic of the Sustainable Development Goals that was distributed among researchers at Leiden University in the month of November 2021.

Metals surfaces form a group of effective catalysts for the reaction of small molecules such as hydrogen (H2).

Inactivating mutations in BRCA1 or BRCA2 genes predispose to several types of cancer.

The development of new environmentally sound technologies is seen as a key route towards achieving sustainability.

“Temminck’s Order” is the scientific biography of Coenraad Jacob Temminck (1778–1850), a Dutch naturalist and the first director of ’s Rijks Museum van Natuurlijke Historie in Leiden.

The AT-Hook Nuclear Localized 15 (AHL15) gene belongs to a plant-specific gene family of DNA-binding proteins. Overexpression of AHL15 in Arabidopsis thaliana delays developmental phase transitions whereas its loss of function causes a slight acceleration.

Hospital pharmacies face significant challenges: the demand for sterile drug reconstitutions is increasing, while specialized personnel remain scarce. Automation offers a potential solution, but its practical implementation in hospitals is still unclear.

This thesis studies the geometry of representation varieties and character stacks. These are spaces parametrizing the representations of a finitely generated group, typically the fundamental group of a compact manifold, into an algebraic group G.

Microbiome composition of the spermosphere and the rhizosphere of wild and modern bean accessions grown in an agricultural and a native soil from Colombia was characterized by metagenomics and cultivation-dependent approaches.

Op 7 december 2021 verdedigde Georgina Kuipers het proefschrift 'Beschadigd vertrouwen'. Het promotieonderzoek is begeleid door prof.mr. W. den Ouden en prof.dr. M.A. van der Steen (EUR).

Promotor: J. Zaanen

The key characteristic of active matter is the motion of an emergent collection (such as a flock of birds), which is driven by the consumption of energy by its active components (i.e. individual birds).

Promotor: Prof.dr. M.L. van Hecke, Co-Promotor: V. Vitelli

A key step in the synthesis of oligosaccharides and glycoconjugates is the formation of the glycosidic bond.

Image segmentation is a fundamental task in computer vision, with applications ranging from medical diagnostics to archaeological research.

Promotor: Prof.dr. D. Bouwmeester

Drug development critically depends on preclinical models that mimic human physiology, yet traditional two-dimensional cultures and animal models often lack predictive power.

Factoren van invloed op arbeidsparticipatie onder mensen met multiple sclerose

GLOBOX is a spatially differentiated multimedia fate, exposure and effect model. It is used for the calculation of spatially differentiated LCA characterisation factors on a global scale.

The project

Kiemproject: Hoe kunnen metaforen bijdragen aan betere maatschappelijke betrokkenheid bij quantumwetenschap en -technologie, en welke factoren beïnvloeden de acceptatie of weerstand tegen metaforen bij zowel experts als leken?

In this course, you will gain a deep insight into the rules that govern armed conflict, and aim to mitigate human suffering on the battlefield. You will explore the why and how of International Humanitarian Law, followed by the different types of conflict.

The Minor in Business Administration teaches business knowledge and skills that are important for your future career.

uman skin equivalents (HSEs) are in vitro 3D-skin models that mimic many aspects of the native human skin (NHS) and can be a valuable tool.

There is no human society that does not employ a rich and diverse language. This course introduces you to linguistics, featuring interviews with well-known linguists and with speakers of many different languages. Join us to explore the miracles of human language!

Promotie

Lezing, LACG Meetings

Promotie

Een masteropleiding vergroot je kansen op de arbeidsmarkt en opent deuren naar uitdagende functies. Na je driejarige bachelor kun je direct doorstromen naar een één- of tweejarige master aan de Universiteit Leiden of een andere instelling.

Een masteropleiding vergroot je kansen op de arbeidsmarkt en opent deuren naar uitdagende functies. Na je driejarige bachelor kun je direct doorstromen naar een één- of tweejarige master aan de Universiteit Leiden of een andere instelling.

Een masteropleiding vergroot je kansen op de arbeidsmarkt en opent deuren naar uitdagende functies. Na je driejarige bachelor kun je direct doorstromen naar een één- of tweejarige master aan de Universiteit Leiden of een andere instelling.

Een masteropleiding vergroot je kansen op de arbeidsmarkt en opent deuren naar uitdagende functies. Na je driejarige bachelor kun je direct doorstromen naar een één- of tweejarige master aan de Universiteit Leiden of een andere instelling.

This research project studies the distribution and impact of medieval malaria in the Netherlands.

What are the pressing issues of our time, and how can different disciplines come together to address them? Studium Generale and Leiden University College (LUC) present the Global Challenges series: events that bring together researchers from LUC and experts from other disciplines to tackle a shared…

The thesis introduces three methods for high-dimensional prediction problems in the biomedical field. The methods make use of empirical and variational Bayes in the estimation.

Het project is gefinancierd door SoFoKleS en mede mogelijk gemaakt door steun vanuit en samenwerking met de Universiteit Utrecht en verschillende partijen binnen de Universiteit Leiden.

This thesis investigates how non-genetic factors, such as inflammation and concomitant medication, impact hepatic drug metabolism and subsequent drug metabolizing phenotype predictions.

Promotor: R. Tijdeman, Co-promotor: C. Kraaikamp

Promotor: H.S. Overkleeft, Co-Promotor: B.I. Florea

The dissertation describes TEM experiments on heterogeneous catalysts.

Promotie

Promotor: G.A. van der Marel, Co-promotor: J.D.C. Codée

Studievoorlichting

Promotor: Prof.dr. M. Schilthuizen

This dissertation presents a new perspective on the life, work and character of the Dutch physical chemist Jacobus Henricus van ’t Hoff, first recipient of the Nobel Prize in Chemistry, and one of the most important and colourful scientists in Dutch history. The image of Van ’t Hoff that emerges from…

This thesis aims to demonstrate how the achromatic nature and design flexibility of liquid-crystal optics can be used to improve high-contrast imaging instruments to facilitate detailed exoplanet characterization.

In the last decades, activity-based protein profiling (ABPP) has emerged as a powerful chemical tool that may aid the ever-challenging drug discovery process.