Jan van den Berg heeft zij proefschrift op 8 november 2018 verdedigd.

This thesis describes biochemical investigations of glucocerebrosidase (GBA), the lysosomal β- glucosidase that is deficient in Gaucher disease (GD).

Promotores: H.A. Udo De Haes, P.M. Brakefield

Promotor: A. Achúcarro, Co-promotor: A. Boyarsky

Promotores: J. Zaanen, A. Parnachev

The work presented in this thesis is based on ALMA surveys of protoplanetary disks in three star-forming regions: Lupus, OMC-2, and NGC 2024.

This thesis is about the study of hydrocarbons via infrared spectroscopy.

Despite the fact that gold nanoparticles (GNPs) are one of the most studied nanoparticles, there is still a necessity for new approaches allowing for effective protective coating to enable wider use of GNPs in biomedical applications.

In meta-analysis, heterogeneity often exists between studies. In such cases, it is essential to investigate the sources of heterogeneity and understand the relationship between effect size and study characteristics (i.e., moderators).

The stratum corneum is the outermost skin layer and consists of dead cells embedded in a lipid matrix.

Scattering of light in the presence of nano-structured materials, i.e. with features in the order of the wavelength of the light or smaller, reveals details of how light interacts with matter at the nanoscale.

Freshwater and brackish water ecosystems are arguably the most vulnerable ecosystems on earth, due to concentrated human developments in and around them. The Pontocaspian (PC) region located at the border of Europe and Asia contains a variety of brackish water ecosystems and unique inhabitants, known…

Promotor: K. Kuijken, Co-Promotor: H. Hoekstra

Growth hormone profiles are pulsatile and highly variable between individuals, limiting the implementation of mathemathical models to quantify an individual's secretion.

Curved single crystals provide variable, but well-defined surface structures.

Promotor: Prof.dr. P. Stevenhagen, Co-promotor: B. de Smit

Promotores: Prof.dr. J. Aarts, Prof.dr. J.M. van Ruitenbeek

Promotores: Prof.dr. S.J. Edixhoven, Prof.dr. E. Ullmo (University Paris-Sud)

An Active Galactic Nucleus (AGN) is a highly luminous region at the center of a galaxy, powered by the accretion into a supermassive black hole and emitting energy from radio waves to gamma rays, often outshining the host galaxy.

Promotor: M.T.M. Koper, Co-Promotor: L.B.F. Juurlink

Image segmentation is a fundamental task in computer vision, with applications ranging from medical diagnostics to archaeological research.

Reconstructie van de taalgeschiedenis door onderzoek naar taalverandering.

This ecological community has long been known to affect host biology, and their diverse roles have been further clarified in recent years following numerous studies of animal:microbiota interactions in diverse systems.

A new publication on changes in the relationship between news and their public in Chile

Voltammetry plays a crucial role in modern scientific research by offering valuable insights into the electrochemical properties of materials, with wide-ranging applications in fields such as materials science, energy storage, corrosion studies, and sensor development.

Single-molecule spectroscopy has become a powerful method for using organic fluorescent molecules in numerous applications.

Promotor: Prof.dr. C.W.J. Beenakker

The effects of anthropogenic noise on interactions between predators and their prey are still little understood.

Galaxies in the local Universe fall into two main categories of spirals and ellipticals. In this Thesis, we explore the structural evolution of galaxies into this bimodal distribution.

Natural history collections provide invaluable sources for researchers with different disciplinary backgrounds, aspiring to study the geographical distribution of flora and fauna across the globe as well as other evolutionary processes.

Stellar feedback is a crucial ingredient in the evolution of galaxies.

Within the field of astronomy, understanding how galaxies grow and evolve from the Big Bang to the present day is a challenging and complex question.

Promotores: Prof.dr. H Lenstra, Prof.dr. A Facchini (Padova University)

One of the key discoveries in exoplanet research over the past decade is the abundance of small planets in our Milky Way. Despite their high numbers, our understanding of their atmospheres remains limited, and it is unknown if they possess atmospheres at all.

This thesis explores different avenues to develop insurmountable antagonists for CC Chemokine Receptors, such as CCR1, CCR2 and CCR5.

Promotor: Prof.dr. A.W. van der Vaart

Planets are formed in disks of gas and dust around young stars.

Promotores: Prof.dr. W.J.G.M. Peijnenburg & Dr. M.G. Vijver

This dissertation is organised into three parts, each addressing a distinct research area related to Gibbs measures.

This thesis investigates how cell shape and collective behavior influence the dynamics and structure of biological tissues, which are crucial for understanding processes like embryonic development, tissue regeneration, and metastasis.

Heart failure is a major health care problem with high mortality.

Promotor: E. Gittenberger, Co-promotor: B.W. Hoeksema

Fundamental research in the ALgebra, Geometry And Number Theory

Plant diversity is essential for us and our planet as it sustains the stability of our ecosystems, provides vital materials and food to us and supports many ecosystem services.

Mechanical forces are known to play an important role in bacterial colonies. In this dissertation, we study the self-organization at various stages of growing bacterial colonies, and focus on the mechanical effects of cell growth.

In this thesis, I focused on studying the above- and belowground interactions of J. vulgaris from a plant-soil feedback (hereafter, PSF) perspective. I investigated the temporal variation of negative PSF and examined the effects of root-associated bacteria on plant performance and aboveground herbiv…

For many system in statistical physics the microcanonical and canonical ensemble are equivalent in the thermodynamic limit, but not for all.

The objective of this study was to investigate the expression and function of GRHL2 in different breast cancer subtypes.

Supervisor: S.F. Portegies Zwart Co-Supervisor: A.G.A. Brown

The subject of this thesis, ‘Approach to Markov Operators on Spaces of Measures by Means of Equicontinuity’, combines an analytical and probabilistic approach to Markov operators.