Cardiovascular diseases are a leading cause of death worldwide, and better models are urgently needed for disease progression studies and drug development.

The function of TLRs in innate immunity has aroused worldwide attention soon after its discovery. Because of the broad functions of TLR2 in innate immunity, the drive for the development of TLR2-targeted vaccines or therapeutic treatments has accelerated in the last decades.

De World Data Visualization Prijs 2019 is uitgereikt aan Dimiter Toshkov, UHD bij Bestuurskunde. Hij ontving de prijs voor de weergave van zijn onderzoek naar kleine staten en good governance. De prijs is een goede manier om mensen bewust te maken van het belang van goede data visualisatie.

Promotores: T.H.W. Bäck, A. Plaat, Co-promotor: F.J. Verbeek

Promotor: Prof.dr. J.A. Bouwstra, Co-promotor: A. El Ghalbzouri

Van 11-13 december 2018 was Hans-Martien ten Napel uitgenodigd om deel te nemen aan een kleinschalig seminar over bovengenoemd onderwerp. Het seminar werd georganiseerd in het kader van het ‘Tradition Project’ van St. John’s University School of Law in New York, mede georganiseerd door Villanova School…

Als interdisciplinair instituut op het gebied van Security Studies onderzoekt het Institute of Security and Global Affairs (ISGA) een breed scala aan onderwerpen. Een daarvan is de Verenigde Naties en de impact die deze internationale organisatie heeft op de wereld.

De shortlist voor de Prof. Dr. J.Th.J. van den Berg-prijs 2019. Wie schreven de beste politicologische bachelorscripties?

Studenten van de Advanced MSc in International Relations and Diplomacy bezochten de OPCW en het ICJ in Den Haag en kregen inzicht in toonaangevende internationale organisaties.

Abeer Abazeed, promovendus aan het Institute of Security and Global Affairs, verdedigt op woensdag 21 april haar proefschrift. Vier vragen over haar promotie-onderzoek 'Is it One Nile? Civic engagement and hydropolitics in the Eastern Nile Basin’

Onderzoekreeks van de Afdeling Economie van de Universiteit Leiden op het raakvlak van economie en recht.

Wat is de staat van het in 2014 opgerichte Nederlandse Defensie Cyber Commando (DCC)? In de nieuwe editie van Atlantisch Perspectief neemt Sergei Boeke het DCC onder de loep en plaatst hij een aantal kritische kanttekeningen.

Van maandag 10 tot woensdag 12 juni 2019 vertegenwoordigden Jeroen Wolbers, Wout Broekema en Sanneke Kuipers het Institute of Security and Global Affairs (ISGA) op de vierde editie van de Noord-Europese Conferentie over Nood- en Rampenonderzoek (NEEDS).

Terreuronderzoekers Bart Schuurman en Liesbeth van der Heide (Institute of Security and Global Affairs) bestudeerden de dossiers van 159 veroordeelden in Nederland in de periode 2012-2017. Hamvraag was: hoe effectief is het speciale reïntegratietraject dat Reclassering Nederland heeft voor dit type…

Promotor: Prof.dr. T.H.W. Bäck

In this thesis, the discovery and optimization is described of chemical tools to study the N-acylethanolamine (NAE) biosynthetic pathway.

Het Institute of Security and Global Affairs (ISGA) biedt onderwijsprogramma’s aan op bachelor- en masterniveau. Tevens zijn er minoren, wordt er online onderwijs aangeboden en is er onderwijs voor professionals.

The ability to count is a property not often attributed to materials, despite the abundance of memory in materials. Regardless of how a material stores information, it is often difficult to retrieve exactly ‘what’ a material remembers.

In the thesis the dynamics of strategies is studied from two perspectives.In the first part of the thesis strategies are considered to be opinions present in a community.

Het onderwijsteam van het Leiden University College The Hague achter het project The Learning Mindset is genomineerd voor De Nederlandse Hogeronderwijspremie, de prijs voor vernieuwend onderwijs in het hoger onderwijs. Het ministerie van Onderwijs, Cultuur en Wetenschap heeft dat op 15 maart bekendg…

In this thesis integral points on affine del Pezzo surfaces are studied.

In deep reinforcement learning, searching and learning techniques are two important components. They can be used independently and in combination to deal with different problems in AI, and have achieved impressive results in game playing and robotics. These results have inspired research into artificial…

Studievoorlichting

Promotor: H.J.M. de Groot

Promotor: P.J.J. Hooykaas, Co-Promotor: E.J. van der Zaal

One of the key limitations of the direct imaging of exoplanets at small angular separations are quasi-static speckles that originate from evolving non-common path aberrations (NCPA) to which the primary adaptive optics system is inherently blind. The main focus of this thesis is the development and…

This thesis describes the design and synthesis of fragments of various cell wall carbohydrates of the Streptococcus species, including the branched Group B-specific antigen (GBC) of Group B Streptococcus, glycerol phosphate (GroP) modified group A carbohydrate (GAC), and the O-acetylated type 1 capsular…

Materials with strongly correlated electrons show some of the most mysterious and exotic phases of quantum matter, such as unconventional superconductivity, quantum criticality and strange metal phase.

Promotor: Prof.dr. M.A.G.J. Orrit

The overarching clinical aim of this thesis was to improve pharmacological pain management by characterizing the pharmacodynamics of analgesics. This promotion has been awarded the predicate cum laude.

In this thesis, a system pharmacology approach, integrating metabolomics, pharmacology and chemical biology, was applied to understand and modulate the endocannabinoid system across different model systems (cells, zebrafish, mice and humans).

Urbanisation is steadily increasing with estimates expecting that 68% of the global population will live in cities by 2050. To accommodate the rural to urban transition, large quantities of land are transformed from natural to urban lands.

Promotor: Prof.dr. A.P. IJzerman, Co-Promotor: L.H. Heitman

Promotor: A. Achúcarro, Co-Promotor: J.W. van Holten

The formation of stars and planets happens over multiple scales, which can interact. In particular, planet formation happens in the dense, complex environment of star forming regions.

Promotores: Prof.dr. E.A.L. Biessen, Prof.dr. T.J.C. van Berkel

Microbial rhodopsins are photosensitive pigments implemented in the growth and adaptation of a large population of microorganisms.

The physical origin of the dozens of stellar-mass binaries, the mergers of which have been detected by the LIGO-Virgo-KAGRA collaboration via gravitational waves, is still unknown.

This thesis describes the design and development of subunit‐selective inhibitors of particular catalytically active subunits of human constitutive proteasomes and immunoproteasomes.

Outflows are crucially important for the gas budget and evolution of luminous star-forming galaxies and AGNs, with observed mass outflow rates of the same order as the star formation rate. Greater star formation and black hole growth lead to more intense feedback and outflows, resulting in self-regulated…

Lezing, LUCL Colloquium

Promotores: G.A. Persoon, H.H. de Iongh

The research provides insight into disease behavior in both rural and semi-urban areas in Serengeti in Tanzania.

A series of workshops at Leiden University and the University of Hamburg will act as a forum in which international legal scholars whose research adopts a behavioural approach can present their works-in-progress and gain feedback from a broad range of peers, including scholars in economics and cognitive…

Arithmetic geometry concerns the number-theoretic properties of geometric objects defined by polynomials. Mathematicians are interested in the rational solutions to these geometric objects.

Business Process Model and Notation (BPMN) has become the standard for business processes diagrams.

Promotor: Christoph U. Keller, Co-promotores: Matthew A. Kenworthy, Frans Snik

This thesis describes how to scale down concepts of macroscopic mechanical metamaterials to the thermal scale using a system of flexibly-linked colloids.

Op 29 februari verscheen er een column van Maaike Warnaar in de Volkskrant over de Iraanse verkiezingen.

Ooit wilde student Lelani Antar naar de filmacademie. Het werd uiteindelijk International Studies, maar toch zei ze film niet helemaal gedag. Voor haar minor maakte ze samen met drie anderen een essayfilm.