The work done during this PhD research, aims to investigate the effect of tidal heatingin the observability of extra-solar satellites around exoplanets.

Promotor: F.S. de Boer Co-promotor: P. T. de Gouw

Promotor: Prof.dr. S.F. Portegies Zwart

A common method to solve expensive function evaluation problem is using Bayesian Global Optimization, instead of Evolutionary Algorithms.

With the advent of multicore processors and data centers, computer hardware has become increasingly parallel, allowing one to run multiple pieces of software at the same time on different machines. Coordination of these pieces is best expressed in a coordination language as an explicit interaction protocol…

Complex Organic Molecules (COMs) have been detected in objects across different stages of stellar evolution.

Low-mass main-sequence stars like our Sun are continuous sources of outflowing hot magnetised plasma. In the case of the Sun, this is known as the solar wind, whereas for other stars they are called stellar winds.

This dissertation combines the use of defined microenvironments, high-resolution fluorescence microscopy, and time-resolved analysis, to study intracellular and cellular motility.

In this thesis, the research focuses on the properties of dark matter and dark matter haloes and how they connect with the galaxies we can observe in the Universe.

In this thesis we study bistable reaction-diffusion equations on lattice domains.

Promotor: Prof.dr. G.R. de Snoo, Co-promotor: R. Heijungs

Promotores: Prof.dr. H. van Veen & Prof.dr. W. de Boer (Wageningen University)

Promotor: Johan Kuiper, Co-promotor: Saskia C.A. de Jager

Consequences for sediment stability and seston trapping

Promotor: G.J. Kramer Co-Promotor: E.G.M. Kleijn

Promotor: R. Gill, Co-promotor: P. Massart

Prostate cancer (PCa) is one of the most prevalent cancer in males.

De Cleveringaleerstoel is ingesteld door de Universiteit Leiden ter herinnering aan hoogleraar Rudolph Pabus Cleveringa en zijn moedige optreden in november 1940 tijdens de Duitse bezetting en ter herdenking van de bevrijding in 1945.

Promotor: P. J. J. Hooykaas Co-promotor: B. S de Pater

Promotores: Prof.dr. G.A. Persoon & Prof. dr. H.H. de Iongh

Plant architecture has distinct forms in different plant species, but also within a species the finalarchitecture of a plant is determined by its gradual development and changes therein induced by environmental conditions during the plant’s life cycle.

This thesis describes the structural and biochemical characterization of the β-lactamase BlaC from Mycobacterium tuberculosis (Mtb), and the Alr and YlmE proteins from Streptomyces coelicolor A3(2).Mtb is the main cause of tuberculosis.

This thesis presents the systematics, epidermal defense, and bioprospecting of wild orchids.

Promotor: Peter Stevenhagen

Promotor: A.P. IJzerman

Promotores: Prof.dr. C.A.M.J.J. van den Hondel, Prof.dr. V. Meyer (Technische Universität Berlin)

The main focus of the thesis is the discovery and development of novel inhibitors of bacterial metallo-β-lactamases (MBLs).

To improve cancer treatments, personalized medicine approaches have aimed to identify exactly which mutations are driving tumor development in a given patient and specifically target these mutations using precision therapies.

The soil ecosystem consists of the largest reservoir of biodiversity on Earth.

Promotor: A.P. IJzerman

Promotores: Prof.dr. H.S. Overkleeft, Prof.dr. G.A. van der Marel

Multi-objective evolutionary computation aims to find high quality (Pareto optimal) solutions that represent the trade-off between multiple objectives.

Promotores: J. Kok, M. Chaudron (Chalmers University)

In this thesis, we extend the concept of null models as canonical ensembles of multi-graphs with given constraints and present new metrics able to characterize real-world layered systems based on their correlation patterns.

In een tijdperk vóór GoogleDocs en LinkedIn vertrouwden 19e-eeuwse wetenschappers op het schrijven van brieven voor samenwerking, peer-feedback en het opbouwen en onderhouden van academische netwerken.

De afdeling eLaw van de Universiteit Leiden is toonaangevend in Europa in onderzoek naar het snijvlak tussen recht en digitale technologieën.

Hieronder staan enkele ervaringen van duale promovendi die gepromoveerd zijn met steun van het Dual PhD Centre.

De Universiteit Leiden reikt regelmatig eredoctoraten, onderscheidingen en prijzen uit.

Archeologe Hayley Mickleburgh onderzoekt hoe lijken ontbinden. Dat helpt bij de reconstructie van veranderingen in begrafenisrituelen van Caribische indianen.

Vanaf een lanceerinstallatie in Frans Guyana gaat op 19 december de Europese satelliet Gaia de ruimte in om een zeer gedetailleerde driedimensionale kaart van het Melkwegstelsel maken. De Leidse astronoom Anthony Brown leidt het consortium dat de vloed aan meetgegevens gaat verwerken.

The thesis is part of a bigger project, the HEPGAME (High Energy Physics Game). The main objective for HEPGAME is the utilization of AI solutions, particularly by using MCTS for simplification of HEP calculations.

Seagrass is a marine flowering plant with special adaptations to coastal and marine environments, playing a crucial role in providing a wide range of ecosystem services.

This thesis focuses on addressing four research problems in designing embedded streaming systems.

Did the Jochids leave their mark on the Grand Duchy, taking into account that the Lithuanian state was one of the main successor states of the Great Horde in the 16thCentury?

When you have decided to participate in a Summer School of Leiden University, there are some matters you need to know before arrival. Please take a few minutes to read through the information here to find out what you can do from your side to smooth the process.

De opleiding Natuurkunde organiseert op dinsdagavond 31 januari haar driejaarlijkse bijeenkomst voor middelbare schooldocenten. Het programma bestaat uit lezingen over ontwikkelingen in de hedendaagse fysica en de nieuwste initiatieven in de onderwijswereld.