When observing star-forming galaxies, we are not only seeing stellar light, but we also see how this interacts with galactic gas and dust. This thesis contains studies of the stellar, nebular and dust properties of low mass star-forming galaxies.

This dissertation presents the results of the importance of creativity for ICT-students of Dutch universities of applied sciences (in Dutch: hogescholen), and the functioning of training courses that aim to promote creative abilities is highlighted.

Promotor: F. Arbab

Anthropogenic noise negatively affects wildlife in a wide range of taxonomic groups.

Protein–protein complexes are formed via transient states called encounter complexes that greatly influence the formation of the stereospecific complex.

We have conducted a full spectral line survey of the 3-13 micron region of two massive protostars, AFGL 2591 and AFGL 2136, for the first time at high spectral resolution.

Op 11 november 2021 verdedigde Evelien Campfens het proefschrift 'Cross-border Claims to Cultural Objects'. Het promotieonderzoek is begeleid door prof.dr. N.J. Schrijver en prof.dr. W.J. Veraart (VU Amsterdam).

Promotor: Prof.dr. S. Portegies Zwart

Het onderzoeken van medische experimenten op mensen in de koloniale periode in Zuidoost-Azië.

Triple-negative breast cancer (TNBC) constitutes a small subtype (~15%) of breast cancer, but causes the majority of breast cancer-related deaths.

Subproject of the ERC project 'Challenging the Liberal World Order from Within: The Invisible History of the United Nations and the Global South'.

This thesis describes the role of pollution, specifically neonicotinoid insecticides, as an actor of the ongoing biodiversity decline.

The effective treatment of tuberculosis (TB) remains a major challenge to global health.

This research focuses on the distribution of chemical elements in protoplanetary disks, the birthplaces of planets. These disks form around young stars and contain gas and dust, from which planets grow. Ice plays a crucial role in planet formation, aiding the clumping of dust particles and influencing…

Promotor: J. Aarts

The main goal of the research described in this thesis was the development of new photoactivated chemotherapy (PACT) ruthenium(II) complexes bearing a non-toxic photolabile ligand.

In today's volatile market environments, companies must be able to continuously innovate. In this context, innovation does not only refer to the development of new products or business models but often also affects the entire organization, which has to transform its structures, processes, and ways of…

Streptomyces present a valuable platform for natural product discovery. Lugdunomycin is a novel angucycline-derived polyketide from Streptomyces sp QL37, with unprecedented skeleton and antimicrobial activity.

The adenosine receptors are proteins that reside in the extracellular membranes of cells. Activation of adenosine receptors plays a role in many physiological and pathological processes, such as immune responses and cancers.

One of the main challenges in the development of an effective anti-cancer vaccine is the generation of an adequate and directed cellular immune response.

Promotores: Prof.dr. H. van Veen & Prof.dr. W. de Boer (Wageningen University)

De Faculteit der Wiskunde en Natuurwetenschappen is gevestigd op verschillende locaties in het Bio Science Park Leiden.

In this thesis, we describe the latest advances in SQUID-detected Magnetic Resonance Force Microscopy (MRFM).

Op 13 januari 2022 verdedigde Pie Habimana het proefschrift 'Harmful Tax Competition in the East African Community'. Het promotieonderzoek is begeleid door prof.dr. H. Vording en prof.dr. S.C.W. Douma (UvA).

Promotor: Bas Edixhoven, Promotor: Qing Liu

Tijdens de vroege moderne tijd werden veel middeleeuwse manuscripten in stroken perkament gesneden, die opnieuw werden gebruikt om de bindingen van nieuw gedrukte boeken te versterken. Tot voor kort kwamen deze hergebruikte stukjes middeleeuwse manuscripten alleen aan het licht wanneer de vroege moderne…

Statistical considerations guide the design and implementation of the experiments that scientists perform. For instance, in a clinical trial about a the efficacy of a treatment, its effect in a certain minimum amount of patients has to be observed in order to make confident assertions about the efficacy…

This proposed research uses ego-documents from visual artists that were not intended for publication to reassess the scholarly debate on the demise of the Russian Avant-garde aesthetic in the twenties and early thirties of the 20th century.

Real-life processes are characterized by dynamics involving time. Examples are walking, sleeping, disease progress in medical treatment, and events in a workflow.

Viral hemorrhagic fever (VHF) is a group of acute diseases caused by highly infectious viruses including Ebola, Lassa, Dengue viruses. Its high mortality rate poses high risk to public health, however, studies on VHF have been hampered due to the non-availability of proper models and incomplete knowledge…

Increasing the efficiency of gene targeting (GT) as a genome editing tool in plants has been an important goal in plant biotechnology.

Promotor: H.P. Spaink, A.H. Meijer Co-promotor: R. Marin-Juez

This thesis involves three topics: benchmarking discrete optimization algorithms, empirical analyses of evolutionary computation, and automatic algorithm configuration.

Promotor: K.J. Batenburg, Co-promotor: A.W. van der Vaart, B. de Smit

Promotor: H.V.J. Linnartz

One of the key limitations of the direct imaging of exoplanets at small angular separations are quasi-static speckles that originate from evolving non-common path aberrations (NCPA) to which the primary adaptive optics system is inherently blind. The main focus of this thesis is the development and…

In most applications, electrocatalysts exhibit a large surface area to volume ratio, for example using nanoparticles.

This thesis explores how electron paramagnetic resonance (EPR) spectroscopy can be used to investigate key biochemical processes.

Particles are omnipresent in biopharmaceutical products. In protein-based therapeutics such particles are generally associated with impurities, either derived from the drug product itself (e.g. protein aggregates), or from extrinsic contaminations (e.g. cellulose fibers).

My PhD project studies how the temporally sequential Hox gene expression is regulated during head-tail patterning of the frog embryo.

This thesis investigates the application of deep learning techniques in image analysis across various domains, focusing on four main themes: feature extraction, classification, segmentation, and integration, demonstrating the transformative potential of these technologies.

Plants, are sessile organisms, have developed strategies to adapt to changes in their environment, in part by altering their growth and development.

Building a Deep Cross-media Transfer Network to extract visual relations that relieve the problem of insufficient training data for visual tasks.

The aim of the research presented in this thesis was to develop new methods forchallenging systems in liquid-state NMR using paramagnetic effects generated by thetwo-armed probe CLaNP-5.

Promotor: S.M. Verduyn Lunel

Understanding the formation and evolution of planetary systems is one of the most fundamental challenges in astronomy. To directly image and study young exoplanets and the circumstellar disks they form from, dedicated high-contrast imaging instruments are built.

Promotor: A. Kros

De programmagroep Leer- en Gedragsproblemen in het Onderwijs doet onderzoek naar stagnaties die kunnen optreden in de cognitieve ontwikkeling.

Promotor: Prof.dr. J. den Hertog

Promotor: H.S. Overkleeft, Co-promotor: M. van der Stelt