35 zoekresultaten voor “Flaubert Gustave 1821 1880 B uuml cherwahn novelle” in de Publieke website
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Identification of novel targets in prostate cancer progression
Promotor: B. van de Water, Co-promotor: E.H.J. Danen
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B cell modulation in atherosclerosis
Cardiovascular disease is a major global burden and atherosclerosis is the main underlying pathological process.
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Witnessing the Process of Bacterial Cell Death: Novel Antimicrobials and Their Mechanisms of Action
This thesis describes the antimicrobial discovery strategy developed in our group, the den Hertog Group at the Hubrecht Institute. It includes a cultivation-based screening approach for novel antimicrobial agents from the source of fungi, and a bacterial time-lapse imaging approach for antimicrobial…
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Novel formulations and delivery strategies for inactivated polio vaccines : new routes with benefits
This thesis describes the development of improved formulations and alternative delivery strategies for polio vaccination.
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Herschrijven en terugschrijven
Schrijvers in dialoog met hun voorgangers
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Triblock polypept(o)ides for siRNA delivery: unique polymeric designs for versatile carrier systems
Utilizing the polymeric platform of polypept(o)ides, this thesis describes synthesis and investigation of novel triblock copolymers to obtain carrier systems with multiple compartments for efficient siRNA delivery. Although the individual microstructure of nanoparticles differs depending on the polymeric…
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Identification of Therapeutic Targets and Antisense Oligonucleotide Mediated Exon Skipping Based Therapies in Arthritis
Promotor: G.J.B. van Ommen
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Chemical Synthesis of Fragments of Streptococcal Cell Wall Polysaccharides
This thesis describes the design and synthesis of fragments of various cell wall carbohydrates of the Streptococcus species, including the branched Group B-specific antigen (GBC) of Group B Streptococcus, glycerol phosphate (GroP) modified group A carbohydrate (GAC), and the O-acetylated type 1 capsular…
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Less is more: reduced mycelial heterogeneity for improved production of enzymes and antibiotics
Hoe kan de techniek van cell wall engineering worden ingezet zodat de industrie streptomyceten beter kunnen verwerken tot nieuwe antibiotica?
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Cholesterol metabolism and hematopoiesis interaction in atherothrombosis
Cardiovascular disease is the leading cause of death worldwide.
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Identification and characterization of developmental genes in streptomyces
Promotor: Prof.dr. G.P. van Wezel
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Interactive scalable condensation of reverse engineered UML class diagrams for software comprehension
Promotores: Prof.dr. J.N. Kok, Prof.dr. M.R.V. Chaudron (Chalmers Univ., Sweden)
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Quantitative pharmacology of antimicrobials
Antimicrobial drugs constitute a fundamental part of modern medicine. The global rise in antimicrobial resistance poses a major threat to global health.
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Role of integrin adhesions in cellular mechanotransduction
Promotor: B. vd Water, T. Schmidt, Co-Promotor: E.H.J. Danen
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Topology and Geometry in Chiral Liquids
We study the interplay of topology and geometry with chirality for several passive and active systems, employing both analytical and numerical methods.
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High throughput microscopy of mechanism-based reporters in druginduced liver injury
Promotor: B. van de Water
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Management of small-scale -African fisheries: The Case of Elephant Marsh in Malawi
How does the management of Elephant Marsh Fishery in Malawi relate to wider contexts of policies, theories and regions? And how can the current management system be adapted to achieve long-term sustainability of the fishery?
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Neerlandistiek over disciplinaire grenzen
Door de steeds verdergaande wetenschappelijke specialisatie kunnen zelfs vakbroeders van elkaar vervreemd raken. Op woensdag 12 januari vindt in Leiden het derde neerlandistische Cross-over Congres plaats. Vakgenoten praten er met elkaar én met vertegenwoordigers van andere disciplines zoals de filosofie,…
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In vivo modelling of Ewing sarcoma in zebrafish
Promotores: Prof.dr. P.C.W. Hogendoorn & Prof.dr. H.P. Spaink Co-promotor: Dr. B.E. Snaar-Jagalska
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The structure of a working catalyst: from flat surfaces to nanoparticles
Promotor: Prof.dr. J.W.M. Frenken
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An Algebra for Interaction of Cyber-Physical Components
Modeling and analysis of cyber-physical systems are still challenging. One reason is that cyber-physical systems involve many different parts (cyber or physical), of different nature (discrete or continuous), and in constant interaction via sensing and actuating.
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Corporate venture management in SMEs: evidence from the German IT consulting industry
Promotor: Prof.dr. B.R. Katzy, Prof.dr. H.J. van den Herik, Prof.dr. G.H. Baltes (University of Applied Sciences Konstanz)
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Exploring the mechanisms of metastatic onset for novel treatment strategies
Promotie
- Publicaties
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Towards artificial photosynthesis: resolving supramolecular packing of artificial antennae chromophores through a hybrid approach
Promotor: H.J.M. de Groot
- PhD candidate in Statistics and Pharmacometrics
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Assistant professor "Inflammation pathways in atherosclerosis"
Wiskunde en Natuurwetenschappen, Leiden Academic Centre for Drug Research (LACDR)
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Publicaties
Publicaties die verschijnen in het kader van het onderzoeksproject Zelfredzaamheid en sociale bescherming over de levenscyclus.
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De postkoloniale podcast: Internationale perspectieven op (post)koloniale literatuur - met Marijke Denger en Elleke Boehmer
Het kolonialisme was niet uniek voor Nederland. Ook andere Europese landen koloniseerden gebieden buiten Europa. Dat leverde Franse, Duitse, Spaanse, Portugese, Italiaanse en Deense, maar vooral veel Engelstalige, koloniale literatuur op.
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Postdoc Computational Modeling for Drug Safety Prediction
Wiskunde en Natuurwetenschappen, Leiden Academic Centre for Drug Research (LACDR)
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14 Veni's voor Leidse wetenschappers
14 veelbelovende Leidse onderzoekers kunnen de komende jaren hun onderzoeksplan realiseren dankzij een Veni-financiering van NWO. De subsidies zijn dit jaar onder meer toegekend aan onderzoek naar de invloed van lawaai op het functioneren van koolmezen, voorwaarden voor de evolutie van leven op planeten,…
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Wetenschappelijke publicaties
Onder vindt u de wetenschappelijke publicaties van het Navigatie Lab Leiden
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Miljoenen mensen te helpen met nieuwe synthetische huidcrème
Een team onderzoekers is erin geslaagd de meest natuurlijk huidcrème die er bestaat, na te maken. Met behulp van de DUBBLE bundellijnen (Dutch Belgian Beamline) bij de European Synchrotron Radiation Facility (ESRF) in Grenoble waren de onderzoekers in staat de samenstelling en de structuur van vernix…
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Research Seminar Series
For questions and suggestions regarding the series, please contact prof. dr. Olaf van Vliet or dr. Max van Lent
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An Algebra for Interaction of Cyber-Physical Components
Promotie