3,322 zoekresultaten voor “organic in a di singapore” in de Publieke website
-
Stereoelectronic and conformational effects in oxocarbenium, iminium and iminosugar ammonium ions
Promotores: Prof.dr. G.A. van der Marel, M. van Heel
-
Applications for activity-based probes in biomedical research on glycosidases
Lysosomal glycosidases are acid hydrolases that fragment glycoconjugates in lysosomes.
-
Photocleavable activity-based acid glucosylceramidase probes
Lysosomal acid glucosylceramidase (GBA1) is a lysosomal enzyme that degrades glucolipids with its main substrate being glucosylceramide (GlcCer). Defects in the GBA1 gene lead to glycosphingolipidosis Gaucher disease (GD), in which the hydrolysis of GlcCer is impaired and therefore, it accumulates in…
-
Destroy, Create, Transform and Sublimate. Laboratory Dissociation Studies on Polycyclic Aromatic Hydrocarbons and Analogues
The aromatic infrared bands (AIBs) seen throughout the interstellar medium (ISM) are generally thought to be carried by polycyclic aromatic hydrocarbons (PAHs) and their nitrogen analogues (PANHs).
-
Structure-reactivity relationships in glycosylation chemistry
In a typical glycosylation reaction, a donor is activated to form a (variety of) electrophilic species which can react with a nucleophilic acceptor, following a reaction mechanism having both SN1 and SN2 character.
-
Glycosyl Cations in Glycosylation Reactions
This thesis describes the use of a combined approach of computational and experimental techniques to gain novel insights to understand the glycosylation reaction and its reactive intermediates.
-
Laboratory studies of Water Ice in Space
Astronomical observations of cold regions in the universe show a rich inventory of ices. Part of these ices may end up on planets like our own, but in that journey they will be exposed to considerable amounts of radiation.
-
Synthesis of chemical tools to study the immune system
This thesis describes the synthesis and biological evaluation of TLR2/6, TLR4, TLR7/8 and TLR9 ligands, of which the activity can be conditionally controlled.
-
eV-TEM: Transmission Electron Microscopy with few-eV Electrons
Electron microscopy has become an extremely important techniquein a wide variety of elds.
-
Exploring chemical space in covalent and competitive glycosidase inhibitor design
Glycoside hydrolases (glycosidases/GHs) are widely abundant enzymes in all kingdoms of life and are important biocatalysts that catalyze the hydrolysis of glycosidic linkages in oligo/polysaccharides, glycoproteins and glycolipids with tremendous efficiency
-
The advantages and disadvantages of bioorthogonal proteins
This thesis describes the use of bioorthogonal proteins in immunological settings. It provides an introduction towards the field of protein modification, which was used throughout the thesis for the expression of proteins containing unnatural amino acids.
-
Inhibitors and activity-based probes for β-D-glucuronidases, heparanases and β-L-arabinofuranosidases
Glycosidases (GHs) are enzymes responsible for the degradation of carbohydrates and play many roles in human health and pathophysiology. Often, abnormal levels of glycosidase activity are markedly linked to human pathologies.
-
Synthesis and application of glycans unique to S. Mansoni
Schistosomiasis is an acute and chronic disease caused by blood dwelling parasitic trematodes of the genus Schistosoma, and it is classified as the second most socioeconomically devastating parasitic disease, second only to malaria.
-
Novel detectors and algorithms for electron nano-crystallography
Promotor: Prof.dr. J.P. Abrahams, Prof.dr. M. van Heel
-
Chitin in the fungal cell wall: towards valorization of spent biomass of Aspergillus niger
Aspergillus niger is an important industrial producer of organic acids and enzymes producing large amounts of spent fungal biomass.
-
Applications of Natural Deep Eutectic Solvents to Extraction and Preservation of Biomolecules
The recently introduced nature-originated deep eutectic solvents, so-called natural deep eutectic solvents (NADES) are considered as truly green solvents, which composed of natural ingredients found abundantly in organisms.
-
Targeting bacterial pathogens with next-generation glycoconjugate vaccines
This thesis investigates innovative and classical strategies in glycoconjugate vaccine development to address the growing threat of multidrug-resistant bacterial infections.
-
Titia LoenenFaculteit der Rechtsgeleerdheid
-
Sheila VaradanFaculteit der Rechtsgeleerdheid
-
Clara van DamFaculteit der Rechtsgeleerdheid
-
Suliman IbrahimFaculteit der Rechtsgeleerdheid
-
Eduard PopFaculteit der Archeologie
-
Theo TsomidisFaculteit der Rechtsgeleerdheid
-
Tody UtamaFaculteit der Rechtsgeleerdheid
-
Paola D'anello Peralta
Faculteit der Rechtsgeleerdheid
-
Michael LiuFaculteit der Rechtsgeleerdheid
-
Marijana Saraf
Faculteit der Rechtsgeleerdheid
-
Dominique Rocha Mattos
Faculteit der Rechtsgeleerdheid
-
Emil Babayan
Faculteit der Rechtsgeleerdheid
-
Endri Mykaj
Faculteit der Rechtsgeleerdheid
-
Sanjay Sethi
Faculteit der Rechtsgeleerdheid
-
Priscilla YoviaFaculteit der Rechtsgeleerdheid
-
Fadhilatul HikmahFaculteit der Rechtsgeleerdheid
-
Widya TuslianFaculteit der Rechtsgeleerdheid
-
Kavya Chowdhry
Faculteit der Rechtsgeleerdheid
-
Mia Dambach
-
Robert Okello -
Andika PutraFaculteit der Rechtsgeleerdheid
-
Laila QhistinaFaculteit der Rechtsgeleerdheid
-
Neha GauharFaculteit der Rechtsgeleerdheid
-
Katherine Watson
Faculteit der Rechtsgeleerdheid
-
Vera Wheni SetijawatiFaculteit der Rechtsgeleerdheid
-
Isabel Magaya
Faculteit der Rechtsgeleerdheid
-
Patrick DegryseFaculteit der Archeologie
-
Het raadsel van het Hollands rif
Met illustraties van Mark Verdult
-
Being a guest author for blogs/online reviews: why and how
How does one become a guest author for Nobel Prize winner Dr. Denis Mukwege Foundation? One of our alumni, Mariasole Forlani, can tell you all about it.
-
A cross-sectional study of early language abilities in children with sex chromosome trisomy (XXY, XXX, XYY) aged 1–6 years
Een goede taalontwikkeling is van belang voor de cognitieve en sociale ontwikkeling, om te kunnen communiceren en om te kunnen leren. Als de taalontwikkeling niet verloopt zoals verwacht, kan dit allerlei consequenties hebben. Kinderen met een extra X of Y chromosoom hebben een verhoogd risico op problemen…
-
Contact
Contact opnemen met FSW kan op meerdere manieren. We zijn telefonisch bereikbaar en ons bezoekadres en postadres vind je op deze pagina.
-
Citizenship, Migration and Global Transformations
Europese burgers worden geconfronteerd met uitdagingen op het gebied van globalisering, migratie, technologische ontwikkelingen en klimaatverandering. Deze uitdagingen vergen het uiterste van onderlinge internationale en intergenerationele solidariteit, wat rechtstreeks betrekking heeft op de grondslagen…
-
Terugblik op de Research Day 2025: It Takes a Village – Shaping Interdisciplinary Futures
'Let's make this a twice-yearly tradition!'– a feeling shared by many after the vibrant Research Day. Engagement started early, with participants connecting informally over good coffee before the formal start of the event on 19 November.