This thesis presents pioneering work on the panchromatic emission of some of the most luminous galaxies in the early Universe: star forming galaxies and active galactic nuclei.

Promotor: Prof.dr. A.G.G.M. Tielens

The stratum corneum is the outermost skin layer and consists of dead cells embedded in a lipid matrix.

De nieuwste opleiding van Universiteit Leiden heet Urban Studies. Hoe gaat dat, het opzetten van een compleet nieuwe studie? De bedenkers aan het woord.

This dissertation explores new chemical strategies for the synthesis of self-adjuvanting peptide conjugates and immunomodulatory ligands aimed at targeted activation of the immune system.

Aan de Universiteit Leiden zijn ruim honderd specialisten werkzaam op het terrein van de Middeleeuwen en de Vroegmoderne Tijd. Met ingang van 2017-2018 bundelen zij hun krachten binnen twee keuzetrajecten – Medieval Studies en Early Modern Studies – beide te volgen vanuit bestaande masteropleidingen…

Seminar

In this thesis, we focus on novel proteins/mechanisms that regulate integrin-adhesion mediated mechano-transduction.

This dissertation was to develop effective graphene-based nanofluidic devices by developing scalable fabrication methods and elucidating proton transport mechanisms.

Promotor: Prof.dr. M.T.M. Koper, Co-Promotor: F. Calle-Vallejo

The use of N fertilizers has increased worldwide in the past century. While this increased input of N has increased food productivity, it has also contributed to decreases in biodiversity, soil quality and environmental health, including increases in greenhouse gas emissions.

Kunnen we van quantum-verrassingen quantum toepassingen maken? Kunnen we het leven onderzoeken en opbouwen vanuit de nano-schaal?

Patients share valuable advice and experiences with their peers in online patient discussion groups.

Promotor: Prof.dr. H. J. A. Röttgering, Co-Promotor: M. Haverkorn

De Engelstalige bacheloropleiding Urban Studies ging dit jaar van start, maar wat houdt de opleiding precies in? André Gerrits, hoogleraar International Studies and Global Politics, was te gast bij Sleutelstad om te spreken over deze nieuwe opleiding.

De Universiteit Leiden heeft een nieuw interdisciplinair studieprogramma gelanceerd: Urban Studies. Studenten duiken in dit Engelstalige bachelorprogramma in hedendaagse en toekomstige stedenproblematiek. Het is de eerste studie waarvoor vijf faculteiten de handen ineenslaan.

De bachelor Security Studies heeft een bronzen medaille ontvangen in EW Beste studies 2023. Elk jaar selecteert EW Beste Studies topopleidingen.

Pharmaceutical companies, governments and the general public have become increasingly aware that animal models used in drug testing lack vital aspects to serve as an accurate representation of human biology. As models of the human body should become more physiologically relevant, animal models no longer…

To meet the rising demand for minerals driven by the global shift to clean energy technologies, ensuring responsible and resilient supply chains is critical. Minerals like cobalt, lithium, and nickel for batteries, neodymium and zinc for wind turbines, and indium for solar panels are essential.

The main subject of this thesis is the design and synthesis of paramagnetic molecules for protein studies with NMR and EPR spectroscopy.

Op woensdag 31 augustus 2022 vond de diploma-uitreiking plaats van de BSc Security Studies. De ceremonie werd geopend door programmadirecteur Daan Weggemans.

Promotor: Prof.dr. T. Schmidt, Co-Promotor: S.J.T. van Noort

Actinobacteria are Gram-positive bacteria that have a complex multicellular life cycle and are well known for their ability to produce a wide range of bioactive natural products (NPs).

Adenosine diphosphate ribosylation (ADP-ribosylation) is a fascinating post-translational modification (PTM) that plays a role in a variety of cellular processes and is associated with several diseases, including cancer and viral infections.

Waar komen International Studies alumni terecht na hun afstuderen? Maak kennis met Guido, Paulien en Lennart. Zij deden alle drie de bachelor International Studies aan de Universiteit Leiden in Den Haag en zijn na hun studie in heel verschillende sectoren terechtgekomen.

Programma directeur van het bachelorprogramma Security Studies Daan Weggemans trapte vanmiddag het eerste webinar voor studiekiezers af. In Kaltura Live had hij een internationaal publiek van zo’n 60 geïnteresseerden.

Carbohydrates, or sugars, are the most diverse and most abundant biomolecules known. However, the isolation of carbohydrate samples in sufficient amounts and purity is often impractical or even impossible, so the chemical synthesis of glycosides becomes relevant. The glycosylation reaction, in which…

The adsorption of D2 and CO2 on catalyst surfaces is studied using a molecular beam in ultra-high vacuum.

Promotor: Prof.dr. M. Ubbink, Co-promotor: G. Siegal

In this thesis, two potential therapeutic targets for diabetic nephropathy were dentified and investigated. First, we show that glomerular clusterin is upregulated in diabetic nephropathy and demonstrated that recombinant clusterin protein can protect the podocytes against oxidative stress in vitro.…

Promotor: Promotor: W.Th.F. den Hollander, Co-promotor: V. Sidoravicius.

De Nederlandse krijgsmacht is de afgelopen jaren op vele fronten veranderd. Letterlijk en figuurlijk. Deze uitgave brengt de laatste kennis en inzichten over het functioneren van dit belangrijke instituut bijeen. Een handboek voor praktijk, wetenschap en onderwijs.

The electrochemical hydrogenation reaction is an alternative approach for the transformation of unsaturated bonds without the use of flammable dihydrogen gas.

Congres/symposium, Masterclass

This dissertation revolves around the design and implementation of novel instrumentation and related measurement techniques, at the single molecule level, for use in biophysical research. Chapter 1 presents an introduction to the field of fluorescence-based single molecule measurements. In particular,…

Promotor: Prof.dr. M. Danhof

This dissertation is an experimental study of laser-generated, atmospheric pressure, transient toroidal helium plasmas.

At the moment, over 350.000 chemicals are registered worldwide for production and use. Their application, however, may harm human health and the environment.

The long-held desire - to link structure directly to function and to explain molecular mechanisms based on basic chemical or physical principles - is finally coming closer, satisfying not only our scientific curiosity but also offering new solutions to the many challenges in the field of health, energy…

By training with virtual opponents known as computer generated forces (CGFs), trainee fighter pilots can build the experience necessary for air combat operations, at a fraction of the cost of training with real aircraft.

The expanding population and economic activity are driving up global energy consumption. Simultaneously, there is an urgent need to transition from fossil fuels to renewable sources to mitigate the climate crisis, primarily caused by fossil fuel combustion.

Promotor: A. Achúcarro Co-promotor: A. Boyarsky

The next generation of high-contrast imaging instruments on space-based observatories requires sophisticated wavefront sensing and control in addition to a high-performance coronagraph.

Barrier function is the natural role of the skin. The lipid matrix present in the outermost layer of the skin, the stratum corneum is important for this function.

The transition to electric vehicles (EVs) reduces vehicle emissions to combat climate change. EVs raise concerns regarding the production of lithium-ion batteries and related emissions; while batteries can also provide energy storage services for the electricity system.

This thesis focuses on developing wafer-scale two-dimensional (2D) materials by combining synthesis, transfer, characterization, and device integration of graphene, hexagonal boron nitride (h-BN), and BN-doped amorphous carbon.