The external tissues of plants and animals are colonized by microbial communities termed microbiota. When organisms are exposed to environmental pollutants, these substances will therefore encounter microbiota at the exposure interface.

A remarkable population of short period transiting rocky exoplanets with equilibrium temperatures on the order of 2,000 K has recently been discovered.

Promotor: Prof.dr. J. Kuiper

The overall theme of this thesis is to complement the electrochemical data acquired in fuel cell research with in situ X-ray photoelectron spectroscopy (XPS) and soft X-ray absorption spectroscopy (XAS).

This thesis explores the theoretical and observational properties of distant massive galaxies that harbour active black holes in their centres and shine brightly at radio wavelengths.

This thesis is about augmented reality (AR). AR is commonly considered a technology that integrates virtual images into a user’s view of the real world.

Promotor: Prof.dr. E. Eliel, Co-Promotor: M.J.A. de Dood

This work is dedicated to interpreting in cohomological terms the special values of zeta functions of arithmetic schemes.

The plant hormone auxin regulates plant growth and development through polar cell-to-cell transport-generated maxima and minima. PIN FORMED (PIN) auxin efflux carriers determine the direction of this auxin flow through their asymmetric placement on the plasma membrane (PM).

Even though more than 4000 extra-solar planets are known today, only a small fraction of these has been captured in an image. To better understand the planet formation mechanisms in solar-like environments we started the Young Suns Exoplanet Survey (YSES).

The bacterial cell wall is a nearly universal structure that offers protection and gives the cell its shape. However, environmental stressors, such as cell wall-targeting antibiotics and hyperosmotic conditions, can induce bacteria to shift to a wall-deficient state. It is unknown whether the lack of…

Promotor: M.T.M. Koper, Co-Promotor: L.B.F. Juurlink

Fungal infections pose a significant threat to individuals with compromised immune systems and despite advancements in diagnosis and treatment, they continue to jeopardize patient’s health.

Mechanical metamaterials are carefully engineered materials whose properties are controlled by their structure, not by their composition, which allows using metamaterials to study and control physical effects in detail⁠.

One of the most important correlation functions in physics, especially in cosmology, is the energy density, which describes how much energy is present at each point in spacetime due to matter fields. A key contribution to the energy density of the primordial universe comes from gravitational waves (GWs),…

Promotores: F.H. van Lunteren, F.P. Israel

This thesis addresses the chemical processes that determine the compositions of giant planet atmospheres.

Breast cancer is the most common cancer in women worldwide. Metastasis, the process by which cancer cells spread to other parts of the body, makes treatments less effective. It is important to unravel the mechanism of metastasis.

Promotor: P. J. J. Hooykaas, Co-promotor: R. Offringa

Cathodic corrosion is a relatively unknown phenomenon that can severely etch metallic electrodes at cathodic (negative) potentials.

Promotor: Prof.dr. P. Stevenhagen, Co-promotor: B. de Smit

This thesis pioneers diatom molecular identification and quantification through genome-scale methods, with four key aims: (i) reviewing DNA/RNA sequencing methods in aquatic biomonitoring to highlight their strengths and limitations;

A new publication on changes in the relationship between news and their public in Chile

Galaxies in the local Universe fall into two main categories of spirals and ellipticals. In this Thesis, we explore the structural evolution of galaxies into this bimodal distribution.

Promotor: Prof.dr. C.W.J. Beenakker

In this work, we attempt to answer the question:

Promotor: S.M. Verduyn Lunel, Co-promotor: O. van Gaans

Despite being the object of intense study, embryonic development has been difficult to model due to a number of reasons. First, complex tissues can be comprised of many cell types, of which we probably only know a subset.

Promotor: Prof.dr. T. Hankemeier, Co-promotor: Theo Reijmers

Promotor: Prof.dr. J. Kuiper

Promotores: J.N. Kok, H.J. Hoogeboom

Kinase inhibitors are key therapeutic agents, particularly in oncology, yet their clinical efficacy is often hampered by off-target effects and limited understanding of their cellular target profiles.

This thesis focusses on the temperature structure in protoplanetary disks. The relation between structures seen in the dust and gas-phase molecules is investigated.

Promotor: Prof.dr. W.J.G.M. Peijnenburg

We investigate the buildup of galaxies from various vantage points. The first two chapters focus on the stellar content of galaxies, especially the distribution of stellar masses at birth and potential variations therein in various galactic environments.

Plants are colonized by an astounding number of microorganisms that can provide different life-support functions, including nutrient acquisition and protection against (a)biotic stresses like drought or pathogen attack.

Promotores: B. van de Water; P. Hogendoorn; J. Bovée Co-Promotor: E.H.J. Danen

Cardiovascular syndromes are the major cause of death in Western societies.

Promotor: J.A. van Veen, Co-promotor: E.E. Kuramae

Patterned detectors are an existing technology that can be found in almost all color cameras.

The main aim of this thesis was to unravel the signaling and regulatory networks that drive tumor cell migration during breast cancer metastasis.

Cardiovascular disease is the number one cause of death worldwide. The most important risk factor for developing this disease is high cholesterol levels in the blood.

A modern ship design process is subject to a wide variety of constraints such as safety constraints, regulations, and physical constraints.

This thesis discusses several questions regarding the double ramification cycle as a Chow class on the moduli space of stable n-pointed genus g curves using tools from so-called logarithmic geometry.

Promotor: P.D. Grünwald

The focus of this thesis is how stars like our Sun and planets like Jupiter, Saturn, and Earth are formed.

Promotor: P.G.L. Klinkhamer, Co-Promotores: K. Vrieling, P.P.J. Mulder

We present an extensive study of methods for exactly solving stochastic constraint (optimisation) problems (SCPs) in network analysis. These problems are prevalent in science, governance and industry.

The redox-conversion reaction of metal-disulfide and metal-thiolate complexes are important, as they may shed light on electron-transfer reactions that often occur in Nature.

The type-IV secretion system (T4SS) is a machinery able to transfer DNA and proteins between bacteria and in certain cases also to eukaryotic cells.