Promotor: Prof.dr. H.J.M de Groot, Co-Promotor: A. Alia

As a virtually inexhaustible source, solar energy plays a major role in future global energy scenarios.

Promotores: W. Jiskoot, F. Ossendorp

Promotor: Huub J.M. de Groot, Co-promotor: Francesco Buda

Promotores: Prof.dr. H.S. Overkleeft, Prof.dr. G.A. van der Marel

Almost all bacteria are enveloped by a cell wall that provides cellular protection.

Almost three years after receiving her honorary doctorate, Dr Graça Machel returned to Leiden University. Over the course of two days she spoke with students, researchers, and other interested persons, about human rights – particularly those of women and children – in a world in which these are continually…

This Thesis describes the synthesis of D-alanylated ribitol-based wall teichoic acids from S. aureus to probe their interaction with immune-binding partners.

Studievoorlichting

Studievoorlichting

Studievoorlichting

Studievoorlichting

Studievoorlichting

Promotor: Christoph U. Keller, Co-promotores: Matthew A. Kenworthy, Frans Snik

Neurodegenerative diseases, including Parkinson’s disease (PD), are increasing in prevalence due to the aging population. Despite extensive study, these diseases are still not fully understood and the lack of personalised treatment options that can target the cause of the diseases, rather than the symptoms,…

Promotor: Prof.dr. J.N. Kok

Like a mixture of oil and water, lipid membranes separate into two liquid phases.

Promotores: Prof.dr. F. van Lunteren, Prof.dr. F.S. Gaastra

My PhD project studies how the temporally sequential Hox gene expression is regulated during head-tail patterning of the frog embryo.

n this PhD thesis, the recombination of different atomic lattices in stacked 2D materials such as twisted bilayer graphene is studied. Using the different possibilities of Low-Energy Electron Microscopy (LEEM), the domain forming between the two atomic layers with small differences is studied.

Humans can see the world through the eyes of other humans and imagine what they know, want, and intend. This competence is known as Theory of Mind.

In this thesis, classes of strongly interacting quantum field theories, have been studied.

A novel mathematical model describes spatial-temporal drug distribution within one or more brain units, which are cubic representations of a piece of brain tissue with brain capillaries at the edges.

Sphingolipids are important membrane compounds with a variety of functions. In mammalian cells, different enzymes are involved in the metabolism of sphingolipids, but interruption of this metabolism process leads to different diseases.

Kantorowicz onderzoekt hoe genderstereotypen de perceptie van leiderschapscompetentie beïnvloeden bij verschillende soorten crises.

This study seeks to analyse how job stress could be the result of performing administrative tasks

Dit onderzoek presenteert een vijfstappenplan voor de ontwikkeling van een effectieve gedragsgerichte cyberveiligheidsstrategie.

Vaak wordt gezegd dat een crisis iemands ware aard naar boven brengt. Het coronavirus stelt het multilaterale systeem op de proef. Politicoloog Gisela Hirschmann (Universiteit Leiden) maakt zich zorgen over de toekomst van internationale samenwerking.

In dit artikel onderzoeken Wout Broekema, Wouter Jong en Sara Perlstein het ontwerp en de beoordeling van crisisonderzoeken vanuit een leerperspectief.

De auteurs presenteren een benadering voor het achterhalen van de voorkeuren van de bevolking voor gebruik in de optionele wegingstap in de Levenscyclusanalyse (LCA).

Promotores: Prof.dr. H.P. Spaink & Prof.dr. P.C.W. Hogendoorn Co-promotor: Dr. M.J.M. Schaaf

Pharmaceutical companies, governments and the general public have become increasingly aware that animal models used in drug testing lack vital aspects to serve as an accurate representation of human biology. As models of the human body should become more physiologically relevant, animal models no longer…

Organic molecules in interstellar space are important as they influence the structure of galaxies and star formations. Studying catalytic processes in space allows us to understand how molecular species are formed and chemically evolved in the interstellar medium and solar system objects.

Glycosidases are essential in fundamental biological processes and are responsible for the degradation of most (oligo)saccharides, glycolipids and glycoproteins.

Supply risks are not new. But the aggravation of power conflicts on the international stage coupled with global shifts towards energy transition and digitalization has triggered the next supply risk research era.

Many of our department’s staff members are actively involved in the Empirical Legal Studies lab and strive towards publishing impactful empirical legal research.

In this thesis, we used genetically engineered mouse models and a variety of cell-culture based assays to identify genes and pathways that are involved in the development and treatment of invasive lobular carcinoma (ILC).

This thesis describes a study from both a theoreticaL and an experimental point of view.

Boekpresentatie

Neurodegenerative diseases pose a large medical and societal challenge. The etiology of these diseases is still poorly understood, which makes drug discovery for these diseases difficult.

Barrier function is the natural role of the skin. The lipid matrix present in the outermost layer of the skin, the stratum corneum is important for this function.

Early time-resolved experiments by Frauenfelder on the ensemble of the kinetic rebinding of CO to myoglobin molecules resulted in a stretched exponential relaxa-tion due to a very large spread of the reaction rates of individual molecules.

Promotor: Prof.dr. B.R. Katzy

Promotor: M. Danhof Co-promotor: O.E. Della Pasqua

Promotor: J. A. Bouwstra

Promotor: Jaap Brouwer, Co-promotor: Remus Th. Dame

Marine sponges are important members of reef ecosystems, as they play ecological roles that are essential for the health of the reef.

Arithmetic geometry concerns the number-theoretic properties of geometric objects defined by polynomials. Mathematicians are interested in the rational solutions to these geometric objects.

Understanding how galaxies form, interact, and evolve comes largely from comparing theory predictions with observational data. Numerical simulations of galaxies provide the most accurate approach to testing the theory, as they follow the non-linear evolution of gas and dark matter in great detail and…

Promotor: Prof.dr. M.K. Richardson