The work described in this Thesis is focused on the assembly of oligosaccharide fragments derived from a fungal polysaccharide, galactosaminogalactan (GAG) and fragments of the exopolysaccharide Pel, generated by Pseudomonas aeruginosa.

Plants and soils from natural ecosystems harbor great diversity of soil microorganisms, which could potentially contribute to the sustainability of horticulture. The knowledge about using wild plant species and soil from natural ecosystem to improve the crop health will advance the application of ecological…

In this dissertation iron-based homogeneous catalysts were synthesized, characterized and investigated for water oxidation activity.

This thesis focuses on the social dimensions of crane and wetland conservation in rural landscapes in Kenya, Uganda and Zimbabwe.

This dissertation explores how Large Language Models (LLMs) can effectively and responsibly contribute to complex decision-making processes. By combining AI and human intelligence, Hybrid Intelligence (HI) emerges, allowing the strengths of both humans and machines to be utilized.

Prematurely born neonates require, amongst others, pharmaceutical therapy. Dosing guidelines for these therapies are often based on data from term born neonates or older infants, while these are not necessarily similar to prematurely born neonates.

Promotor: H.J.A. Röttgering, Co-promotor: M. Haverkorn

This thesis addresses the chemical processes that determine the compositions of giant planet atmospheres.

The investigations described in this thesis lay out strategies aimed at advancing antibiotic research and development. The examples presented revolve around two main approaches: understanding drug-target interactions and target identification.

Throughout the history of computer science, a major challenge has been how to assert that software is free of bugs and works as intended. Software bugs can lead to serious negative impacts on any software system. Throughout the main body of the thesis, we implemented a series of studies on exploring…

Over the past years it has been discovered that the population of extra-solar planets is large and diverse.

We have studied shape with a particular focus on the zebrafish model system. The shape is an essential appearance of the phenotype of a biological specimen and it can be used to read out a current state or response or to study gene expression.

Vanaf de koloniale tijd tot heden hebben grote aantallen Javanen hun woonplaats verlaten om zich in andere delen van Indonesië of veel verder weg te vestigen. Vaak was deze spreiding gedwongen, vaak met traumatische gevolgen.

Promotores: Prof.dr. J. Zaanen, Prof.dr. K.E. Schalm

This Thesis describes the synthesis of D-alanylated ribitol-based wall teichoic acids from S. aureus to probe their interaction with immune-binding partners.

Electoral Systems and Turnout: Evidence From a Regression Discontinuity Design. In dit artikel, gepubliceerd op de website SAGE research methods, bespreken auteurs Jaroslaw Kantorowicz en Tobias M. Hlobil hoe een Regression Discontinuity Design uitgevoerd kan worden.

In dit artikel onderzoeken Thijs van Dooremalen en Philip Smith hoe het publieke discours over hittegolven is verschoven in Britse kranten.

Promotor: Prof.dr. A.G.G.M. Tielens, Prof.dr. C. Dominik (UvA)

Nu we weer steeds vaker op kantoor te vinden zijn en het thuiswerkadvies is komen te vervallen, is het van belang om stil te staan bij de keuze om thuis dan wel op kantoor te werken. Velen geven er de voorkeur aan dit af te wisselen.

Heterogeneous catalyzed processes are highly significant to the chemical industry. Dissociative chemisorption (DC) of molecules on surfaces is always considered as a step with a high degree of rate control for heterogeneous catalysis.

Op 9 juni 2020 verdedigde Maral Darouei haar proefschrift 'Managing a sustainable career in the contemporary world of work: Personal choices and contextual challenges'. Het promotieonderzoek is begeleid door promotor prof.dr. J.I. van der Rest.

Hoewel de meerwaarde van stages in het bedrijfsleven in eerder onderzoek wordt onderschreven, is er nog niet veel bekend over hoe het leren van docenten tijdens hun stage plaatsvindt en hoe zij hun leerervaringen uit stages gebruiken voor hun nderwijs. Om een meer diepgaand inzicht te verkrijgen in…

Bernard Bernards onderzoekt beperkingen op innovatie door te focussen op cognitieve onzekerheid als toestand die innovatief werkgedrag kan beïnvloeden.

This dissertation explores how we can make anomaly detection—identifying unusual or faulty behavior in complex systems—more trustworthy and effective, with a focus on smart manufacturing.

For questions and suggestions regarding the series, please contact prof. dr. Olaf van Vliet or dr. Max van Lent

A workshop is organized at St John's College, Oxford, on September 23-24. The workshop aims to bring together medievalists of all disciplines to discuss the research and teaching of ‘difficult’ or ‘taboo’ topics. The organizers welcome applications from scholars working in any field that demands sensitivity…

Van de patiënten met multipele sclerose (MS) krijgt 34-65% vroeg of laat te maken met cognitieve problemen.

Kunst en vrije tijd, Kunst en vrije tijd

The global agri-food system plays a critical role in food security and environmental issues.

Early time-resolved experiments by Frauenfelder on the ensemble of the kinetic rebinding of CO to myoglobin molecules resulted in a stretched exponential relaxa-tion due to a very large spread of the reaction rates of individual molecules.

In this thesis, the role of plant-mediated soil legacy effects in shaping aboveground plant-insect interactions was investigated.

Irene Khan, expert op het gebied van mensenrechten, werpt een aantal vragen op: Wat kan men verstaan onder een ‘Culture of Justice’? Wie bepaalt wat 'Justice' is? Hoe realistisch is de bevordering van ‘Rule of Law’ en ‘Justice’ in landen waar sprake is van ernstige conflictsituaties en armoede?

Na maanden van thuiswerken, hoe vergaat het de medewerkers van het Instituut Geschiedenis? Marlisa den Hartog en Theo Dekker delen hun verhaal.

In astronomy, the interpration of observations and measurements plays a crucial role: we rely purely and fundamentally on the information that reaches us as observers. And 80% of all matter in the universe is undetectable directly.

Wat maakte het vroege islamitische rijk zo succesvol en hebben we het verhaal gemist door cruciaal bewijs te negeren? De Arabische veroveringen in de 7e eeuw veranderden de sociaal-politieke configuraties in het Middellandse Zeegebied en Eurazië voorgoed. Toch weten we niet echt hoe de Arabieren erin…

Francine van Vlijmen, net afgestudeerd in Staats- en Bestuursrecht aan de Universiteit Leiden, heeft op 20 oktober een poster-presentatie gegeven tijdens de conferentie “Reshaping Work in the Sharing Economy” in Amsterdam.

The Hague Journal of Diplomacy (HJD) sluit 2020 af met een gratis uitgave over de impact van de coronacrisis. Dertien auteurs op vier continenten schrijven over ‘Diplomacy after Covid19’.

The high velocity tail of the total velocity distribution of stars provides essential insight into fundamental properties of the Galaxy.

Taxonomy as a science has accumulated data and knowledge for more than 250 years.

Het Nationaal MS Fonds heeft jouw stem nodig voor de beste werkgever voor mensen met multiple sclerose (MS). De prijs is gebaseerd op het onderzoek MS@work van psychologen in Leiden. Stemmen kan tot en met donderdag 14 november; de prijsuitreiking is op 17 november.

Promotor: J.G.E.M. Fraaije, Co-Promotor: A. Kros

Nature uses a special class of histone proteins, histone variants, to modulate the properties of chromatin at defined genomic locations.

Promotor: Prof.dr. T. Hankemeier, Prof.dr. J.C.T. Eijkel (Twente University)

This thesis explores how bees and hoverflies are distributed across the Dutch landscape and how ecological and landscape factors shape their occurrence.

Artin L-functions associated to continuous representations of the absolute Galois group G_K of a global field K capture a lot of information about G_K as well as arithmetic properties of K.

This thesis studies operator-algebraic aspects of subproduct systems, a generalization of product systems of Hilbert spaces.

Lezing

With an emphasis on developing novel miktoarm star polymers termed PeptoMiktoStars, this thesis leverages asymmetric polymeric polypept(o)ide frameworks to advance their effectiveness in delivering hydrophobic drugs and nucleic acids.