How are new drugs developed? This question is central to the Minor Modern Drug Discovery (MDD), which covers the entire trajectory from disease to drug molecule and vice versa. The various research groups involved offer a complementary and interdisciplinary perspective by connecting the diverse subjects…

Drones blijken een goed hulpmiddel om door de mens aangebrachte veranderingen in het landschap in kaart te brengen. Geofysicus Till Sonnemann en zijn collega’s (archeologie) experimenteren ermee in moeilijk doordringbare gebieden in de Cariben.

Promotores: W.T. de Groot, M. Tchuenté, Co-promotor: J.P. Cheylan

Gedeelde identiteit, de vorming van onze jeugd en toekomst, ontwikkeling van wetenschap en techniek: over zulke gevoelige onderwerpen gaat het in het onderzoek naar 100 jaar Ministerie van Onderwijs, Cultuur en Wetenschap (OCW).

Wat betekent de intersoortelijke interpretatie van het gelijkheidsbeginsel voor de democratische rechtsstaat en is het mogelijk dieren een daarbij passende juridische en politieke positie te verschaffen, zonder te breken met de klassiek-liberale uitgangspunten van de democratische rechtsstaat?

Deelproject van

The main object of study in this thesis is an Arakelov inequalitywhich bounds the degree of an invertible subsheaf of the direct image ofthe pluricanonical relative sheaf of a semistable family of curves.

In this thesis, we developed new ways to use a technique called electroextraction (EE) to extract charged molecules from one liquid into another using an electric field.

The main objective of this thesis was to develop clinically relevant survival models for patients with high-grade soft tissue sarcoma of the extremities, in particular the development and validation of prediction models for use in clinical practice.

Metabolomics is a powerful tool that can provide a comprehensive insight into the complexity of human biology and the pathophysiology of diseases. By analyzing the metabolome, which refers to the complete set of small (endogenous) molecules (with a mass <1500 Da) present within a given biological system,…

Light-Harvesting Complex II (LHCII) is responsible for light absorption and excitation energy transfer in plants and photosynthetic algae, while in high light it undergoes conformational changes by which it quenches excitations to prevent photodamage.

The origin and evolution of galaxies are closely linked to many different physical phenomena.

Dissochaeta Blume (Melastomataceae, tribe Dissochaeteae) is well-known as a scrambling plant genus found in Southeast Asia, where it is an inhabitant of the tropical rainforests or evergreen forests.

Cardiovascular diseases are still a major concern for the global health.

Promotor: K.H. Kuijken

In this thesis we have discussed several parameters that affect the electrochemical conversion of enviromentaly harmful molecules such as nitrates and carbon dioxide to more valuable and less deleterious compounds, in order to cast light onto the mechanism of the reaction to achieve an efficient and…

In this thesis, we have studied cell images from two types of cells, including pollen grains and the immune cells, neutrophils. These images are captured using a bright field microscope and a confocal microscope.

Promotor: F. Arbab, R. De Nicola, Co-Promotor: M. Tribastone

A plasma is an ionized gas with very low electrical resistivity. As such, magnetic field lines are 'frozen in' and move with the fluid. Magnetic field lines that are linked, knotted and tangled, cannot be undone by the fluid motions.

Promotor: Prof.dr. P. Stevenhagen, Jan-Hendrik Evertse, Co-promotor: Pascal Autissier

Promotores: Prof.dr. M. Franx, Prof.dr. P.G. van Dokkum (Yale University)

In this PhD study, I aim to deepen our understanding of the influence of major mycorrhizal types, namely arbuscular mycorrhizae (AM) and ectomycorrhizae (EM), on the global soil carbon cycle and their potential distribution changes under future environmental shifts.

This thesis studies operator-algebraic aspects of subproduct systems, a generalization of product systems of Hilbert spaces.

Promotor: S.J. Edixhoven

The main aim of my Ph.D. thesis is to further explore the value of using early developing zebrafish larvae (up to 5 dpf) as a model to study anxiety-like behaviour and their pharmacological modulation with drugs.

Data Science (DS) and Artificial Intelligence (AI) are omni-present and have the potential to be incorporated in various fields. However, in order to live up to this expectation, a good understanding of the techniques, their implications and limitations is required. In this minor you develop insights…

Het is moeilijk om je een andere samenleving voor te stellen dan een hiërarchische natiestaat. Dat komt deels doordat we alternatieve voorbeelden uit het verleden verwaarlozen, betoogt archeoloog Lewis Borck in het Journal of Contemporary Archaeology.

Het huidige bestuur van de Vereniging van Oud-Sterrewachters bestaat uit Niels van Weeren, Maaike Damen, Gerben Zwart en Anthony Brown (contactpersoon Sterrewacht).

Promotor: Prof.dr. J. Kuiper

Promotores: H.A. Udo De Haes, P.M. Brakefield

With the dramatic growth of the image data on the web, there is an increasing demand of the algorithms capable of understanding the visual information automatically.

Promotor: C.A.J. Knibbe, Co-promotor: J.J. Boelens, R.G.M. Bredius

Promotor: Johan Kuiper, Co-promotor: Saskia C.A. de Jager

Multiple stars, that is two or more stars composing a gravitationally bound system, are common in the universe.

Optimization tasks in practice have multifaceted challenges as they are often black box, subject to multiple equality and inequality constraints and expensive to evaluate.

This thesis applies data mining in commercial settings in the telecommunications industry.

Promotor: Prof.dr. P. Stevenhagen

Cardiovascular syndromes are the major cause of death in Western societies.

Astronomical observations of cold regions in the universe show a rich inventory of ices. Part of these ices may end up on planets like our own, but in that journey they will be exposed to considerable amounts of radiation.

Cancer is considered the silent pandemic of the 21st century and the second leading cause of death worldwide.

The main aim of this thesis was to unravel the signaling and regulatory networks that drive tumor cell migration during breast cancer metastasis.

The overall objectives of my thesis are to investigate the dynamics of the sorghum root microbiome and to explore the beneficial effects of the root microbiome on sorghum growth and stress tolerance.

Constraint multi-objective optimization with a limited budget for function evaluations is challenging. This thesis tackles this problem by proposing new optimization algorithms. These algorithms are applied on holistic ship design problems. This helps naval architects balance objectives like cost, efficiency,…

Promotores: P. Stevenhagen, A. Enge Co-Promotor: T.C. Streng

Promotor: P.D. Grünwald