Promotor: B.van de Water, Co-promotor: L.S.Price

Promotor: Prof.dr. G.P. van Wezel

The cannabinoid receptor type 2 (CB2R) is associated with several inflammatory diseases with an unmet medical need (e.g. Alzheimers, multiple sclerosis, reumatoid arthritis). Development of new chemical biology strategies to study this protein is essential to aid future development of drugs for these…

Chinese materia medica (CMM), comprising a diverse array of natural substances from plants, animals, and minerals, has been integral to Traditional Chinese Medicine (TCM) throughout history. This study investigates the dynamic evolution of CMM, noting shifts in species for improved therapeutic effects…

Herken je dat: je ziet je vriend lachen, en plots begin je ook te grijnzen? Promovendus Chris Riddell doet onderzoek naar hoe en waarom we lichaamstaal kopiëren. Hij neemt je als nieuwe Face of Science een jaar lang mee in zijn onderzoek.

Cryogenic electron microscopy (cryo-EM) is a powerful technique used to visualize the inside of cells and to study specific protein complexes. Within this thesis, I describe the use of various cryo-EM techniques to gain insight into the structural changes of the human pathogen, Vibrio cholerae, as it…

A plasma is an ionized gas with very low electrical resistivity. As such, magnetic field lines are 'frozen in' and move with the fluid. Magnetic field lines that are linked, knotted and tangled, cannot be undone by the fluid motions.

Een goede taalontwikkeling is van belang voor de cognitieve en sociale ontwikkeling, om te kunnen communiceren en om te kunnen leren. Als de taalontwikkeling niet verloopt zoals verwacht, kan dit allerlei consequenties hebben. Kinderen met een extra X of Y chromosoom hebben een verhoogd risico op problemen…

Tijdens hackwedstrijd HALON hadden 28 teams één doel: zoveel mogelijk kwetsbaarheden vinden in de systemen van Nederlandse hogeronderwijsinstellingen. Ontwikkelaar onderwijssoftware Chris Handy deed in zijn eentje mee en belandde op de tweede plek in de categorie ‘Vulnerabilities found at the highest…

Cytotoxic T-cells (CTLs) are involved in the clearance of viruses and killing of tumor cells.

Op 19 september 2019 verdedigde Lynette Janssen zijn proefschrift 'EU Bank Resolution Framework: A comparative study on the relation with national private law'. Het promotieonderzoek is begeleid door promotoren prof.mr. W.A.K. Rank en prof.mr. M. Haentjens.

This thesis presents the first synthetic peptides ADP-ribosylated on serine, threonine, tyrosine, arginine and cysteine.

Light-Harvesting Complex II (LHCII) is responsible for light absorption and excitation energy transfer in plants and photosynthetic algae, while in high light it undergoes conformational changes by which it quenches excitations to prevent photodamage.

Promotor: H.S. Overkleeft, Co-Promotor: B.I. Florea

Promotor: Prof.dr. R. Verpoorte, Co-Promotor: Dr. Young Hae Choi

Centraal in dit proefschrift staan de perspectieven van docenten met betrekking tot zelfstandig leren.

β-Lactamases are enzymes that can break down β-lactam substrates, such as antibiotics, preventing the use of these antibiotics for the treatment of various infectious diseases. However, some compounds, β-lactamase inhibitors, can block these enzymes allowing for possible treatments using a combination…

n this PhD thesis, the recombination of different atomic lattices in stacked 2D materials such as twisted bilayer graphene is studied. Using the different possibilities of Low-Energy Electron Microscopy (LEEM), the domain forming between the two atomic layers with small differences is studied.

Including modelling as part of software development appears to have various benefits.

Like a mixture of oil and water, lipid membranes separate into two liquid phases.

Solar energy harnessed by plants and algae has great potential to be converted into biofuels for future generations.

This thesis investigated miniaturized mass spectrometry (MS)-based analytical methods to address challenges in analyzing biomass-restricted biological samples.

Op 10 juni 2021 verdedigde Merinda Stewart haar proefschrift 'Freedom of Overflight: A Study of Coastal State Jurisdiction in International Airspace'. Het promotieonderzoek is begeleid door promotoren prof.dr. P.M.J. Mendes de Leon en prof.dr. J.J. Rijpma.

Op 26 september promoveert Cosmas Rai Amenorvi. Het Leiden University Centre for Linguistics feliciteert Cosmas!

Lezing, Lezingenreeks vergelijkende Indo-Europese taalwetenschap (VIET)

In this thesis the combinatorial use of bioorthogonal labelling and Electron Microscopy (EM)-based imaging techniques is explored to enable observations of specific molecular targets in their ultrastructural context within the cell.

The Copenhagen interpretation of quantum mechanics states that a measurement collapses a wavefunction onto an eigenstate of the corresponding measurement operator.

Een vergelijkende analyse van legitimeringsstrategieën in drie landen: Rusland, Venezuela en de Seychellen.

In dit artikel heeft Lianne Visser bijgedragen aan het begrip rondom samenwerkend bestuur als uitdagende aanpak voor hardnekkige problemen.

On the largest scale, the Universe resembles a cosmic spiderweb. Most galaxies coexist in small groups within the threads of this web. At the nodes of the threads are enormous groups of galaxies forming the largest structures in the universe still held together by gravity: clusters of galaxies.

The demand for neodymium-iron-boron (NdFeB) magnets is rapidly growing, while the neodymium supply chain is under pressure. Recycling can alleviate these issues. This thesis investigates the potential for deploying novel magnet recycling technologies and their environmental consequences.

This thesis focuses on the development of sample-preparation methods for small amounts of samples and applying the developed methods to muscle tissues to investigate the mechanisms involved in sarcopenia.

Hoe beheren humanitaire responsorganisaties (HRO's) en virtuele en technische gemeenschappen (V&TC's) gezamenlijk de processen voor het bepalen van de betekenis van rampen, en welke uitdagingen vormen de effectiviteit van deze samenwerkingen tussen 2010 en 2016?

Promotie

Promotie

Lezing, LUCL Colloquium | Lezingenreeks vergelijkende Indo-Europese taalwetenschap (VIET)

This dissertation focused on computational methods based on first principles calculations using the Density Functional Theory (DFT) framework. Emphasis was laid on affordable methods that can provide a tradeoff between computational expense and accuracy.

The Datini Institute has launched a call for research papers for its 54th Study Week (14-18 May 2023). Deadline for submission: 10 April 2022.

Europese burgers worden geconfronteerd met uitdagingen op het gebied van globalisering, migratie, technologische ontwikkelingen en klimaatverandering. Deze uitdagingen vergen het uiterste van onderlinge internationale en intergenerationele solidariteit, wat rechtstreeks betrekking heeft op de grondslagen…

Dit proefschrift omvat vier deelstudies naar de inhoud en structuur van de opvattingssystemen van natuurkundedocenten over het leren en onderwijzen van natuurkunde in het voortgezet onderwijs (VO) in Nederland.

Op 1 december 2020 verdedigde Bernadette Muscat haar proefschrift 'Insolvency Close-out Netting: A comparative study of English, French and US laws in a global perspective'. Het promotieonderzoek is begeleid door promotoren prof.mr.drs. M. Haentjens en prof.mr. B. Wessels.

A framework for prospective/ex-ante life cycle assessment (LCA) and ecological risk assessment (ERA) of emerging technologies is developed and applied to a case study of III-V/silicon photovoltaic panels.

This dissertation investigates the energy and material related impacts of the transition towards a low-carbon heating system in the Netherlands, in the context of its 2050 climate and circular economy policy goals.

Sound is everywhere in the marine environment and hearing is therefore a very important for stimuli for fish. They use sound for orientation and communication, during migration, aggregation and spawning, but also for detection of prey and predators.

Aan de hand van een reeks case studies in Irak, Moldavië en Servië gedurende het post-Koude Oorlogstijdperk, onderzoekt dit boek asymmetrische conflicten waarbij de strijdende partijen een grote ongelijkheid in machtsposities vertonen.

Prof. dr. Judi Mesman is benoemd tot hoogleraar interdisciplinary study of societal challenges, een gedeelde leerstoel tussen de faculteiten Governance and Global Affairs (FGGA) en Sociale Wetenschappen (FSW) van de Universiteit Leiden.

Promotor: W. Jiskoot, Co-promotor: H.A. Every

A small insight into the annual study trip to Brussels of the advanced master programme Law and Digital Technologies.

Friday 30 January 2015 were the final presentations of the last course of the Minor Sustainable Development.

On June 26-28, 2024, the Annual Conference of the International Society for the Study of Medieval Theology will take place. The theme this year is "The End: Finiteness, Death and Completion in Medieval Theology". Deadline for paper proposals: 20 December 2023.