Self-assembly is an abundant process in nature and is vital to many processes in living organisms.

This thesis applies data mining in commercial settings in the telecommunications industry.

Promotor: J.N. Kok, Co-promotor: C.M. Soares, A.J. Knobbe

Streptomyces present a valuable platform for natural product discovery. Lugdunomycin is a novel angucycline-derived polyketide from Streptomyces sp QL37, with unprecedented skeleton and antimicrobial activity.

This dissertation presents the results of the importance of creativity for ICT-students of Dutch universities of applied sciences (in Dutch: hogescholen), and the functioning of training courses that aim to promote creative abilities is highlighted.

Traditional drug discovery approaches have been hampered by (in vitro) cell-culture models that poorly represent the situation in the human body.

Promotor: E. Gittenberger, Co-promotores: L.P. van Ofwegen; B.W. Hoeksema

Promotor: M.K. Richardson, Co-Promotor: F. Witte

The redox-conversion reaction of metal-disulfide and metal-thiolate complexes are important, as they may shed light on electron-transfer reactions that often occur in Nature.

The Standard Model (SM) of particle physics fails to explain several observed phenomena and is incomplete. In order to resolve this problem, one may extend the SM by adding new particles.

In multi/many-core System-on-Chips (SoCs), the performance is almost linearly scaling with the number of processing elements.

Tracing the evolution of the molecular gas content in galaxies is critical for a complete understanding of galaxy formation and evolution, as it provides the direct fuel for star formation. Studies of high-redshift (z>1) molecular gas reservoirs, most commonly traced by carbon monoxide (CO), have seen…

The project Multimedia Research and Documentation of African Oral Genres: Connecting Diasporas and Local Audiences (Director: D.Merolla) focuses on multimedia as technology that allows scholars to share documentation and scientific knowledge with the cultural owners of the collected oral genres.

Promotores: Wim Jiskoot; Ferry Ossendorp

The research described in this thesis centered on retaining exo-β-glucosidases implicated in health and disease, in particular the human inherited lysosomal storage disorder, Gaucher disease (GD).

International trade has played a major role in defining the modern global economy. Trade, however, entangles the environmental pressures of economic sectors, giving the illusion of environmental improvements, while the opposite may be occurring.

This dissertation is about Bayesian learning from data. How can humans and computers learn from data?

A New Technology-Based Firm (NTBF) is a significant enabler of job creation and a driver of the economy through stimulating innovation.

Promotor: P.J.J. Hooykaas, Co-Promotor: E.J. van der Zaal

The electrochemical oxygen reduction reaction (ORR) is an essential half-reaction for the utilization of hydrogen as a sustainable fuel, via the conversion of hydrogen to electrons and protons facilitated by the ORR. In the most common fuel cells, the ORR is requires high loadings of non-abundant platinum…

An interdisciplinary collection of the best international scholarship on Muslim youth.

Thermodynamics is one of the founding scientific pillars that has helped us better understand heat engines, biology, ecosystems, and even black holes. While it fundamentally describes large systems by examining the bulk behavior of their constituents, it is anchored in the statistical equivalence of…

There are many interpretations of quantum mechanics, and ultimately experiments are needed to verify or falsify these interpretations.

Promotor: Prof.dr. B. van de Water

Phosphorylation affects all four major biomolecules – proteins, lipids, carbohydrates and nucleic acids – and plays a pivotal role in the most fundamental cellular functions.

All crested and marbled newts (the genus Triturus) suffer from an unusual genetic abnormality, called a balanced lethal system, that kills exactly half of their offspring. How can a trait so disadvantageous have survived millions of years of natural selection?

Promotor: Promotor: W.Th.F. den Hollander, Co-promotor: V. Sidoravicius.

The ability to count is a property not often attributed to materials, despite the abundance of memory in materials. Regardless of how a material stores information, it is often difficult to retrieve exactly ‘what’ a material remembers.

Promotor: J. van der Greef, T. Hankemeier; Co-promotor: H.A. van Wietmarschen

Streptomyces are filamentous bacteria that produce more than two-thirds of known antibiotics.

An Active Galactic Nucleus (AGN) is a highly luminous region at the center of a galaxy, powered by the accretion into a supermassive black hole and emitting energy from radio waves to gamma rays, often outshining the host galaxy.

Heart failure is a major health care problem with high mortality.

In this thesis, we have studied the potential of the zebrafish larval model in studying the ECS, as a complementary model to the existing rodent models.

Promotors: W. Jiskoot; G.J. Witkamp, Co-promotor: M.R. Nejadnik

Promotor: A. Kros

Marine sponges are important members of reef ecosystems, as they play ecological roles that are essential for the health of the reef.

Optical projection tomography (OPT) is a tomographic 3D imaging technique used for specimens in the millimetre scale.

Promotor: B.van de Water, Co-promotor: L.S.Price

In my research, I used a comparative wood anatomical approach to address wood evolution of the (largely) tropical flowering plant families Apocynaceae and Sapotaceae.

This thesis describes the development of improved formulations and alternative delivery strategies for polio vaccination.

Op woensdag 16 april vonden twee inspirerende carrière-evenementen plaats aan de Universiteit Leiden: het Humanities Career Event in Leiden en de Job Fair in Den Haag. Samen trokken deze events bijna 1.000 studenten die zich volop oriënteerden op hun carrièremogelijkheden.

Op 7 december won Marlisa den Hartog de Volkskrant-IISG Scriptieprijs voor Geschiedenis. De titel van haar bekroonde werkstuk luidt ‘The Pleasure that is Taken in Bed: Perceptions of Sexual Desire and Sexual Identity in Italy, 1450-1500’. De scriptie van de laureate werd uit 37 inzendingen gekozen.

Ter ere van de 50-jarige samenwerking staat er in 2024 elke maand een artikel in Weekblad Regio Oss over de bijzondere archeologie in Oss. Met deze maand een artikel over Sidney van den Bergh. Sinds hij twee jaar geleden begonnen is als wethouder van de gemeente Oss, is hij erg onder de indruk van de…

De Jaap van den Berge-literatuurprijs wordt jaarlijks toegekend aan een auteur die door middel van publicaties in de vakpers een belangrijke bijdrage levert aan de fiscale rechtsontwikkeling. Stichting NLFiscaal heeft de prijs in 2018 in het leven geroepen. Eerdere prijswinnaars waren Rens Pieterse…

Studying the impact of urbanisation on the respiratory health of past Dutch populations (1200-1850 CE).

Als afsluiting van het keuzevak arbeidsverhoudingen bij de overheid brachten de studenten op 13 mei een bezoek aan Haagse instellingen. Een van de thema’s van dit door prof. J.J.M. Uijlenbroek en prof. B. Barentsen gedoceerde vak is dat van politiek-ambtelijke verhoudingen. Daarom werd het laatste college…

uman skin equivalents (HSEs) are in vitro 3D-skin models that mimic many aspects of the native human skin (NHS) and can be a valuable tool.

De Universiteit Leiden heeft een samenwerkingsverband met de rechtbank Den Haag. In dit verband heeft Annemarie Drahmann op 21 mei jl. een lezing gegeven aan rechters en juridisch medewerkers van de rechtbank over de verdeling van schaarse vergunningen.

Op donderdag 29 november 2018 brachten LLP tutorgroep 27 en 28 een werkbezoek aan advocatenkantoor Pels Rijcken in Den Haag. LLP staat voor Leiden Law Practices en is een verplicht onderdeel van het studieprogramma voor eerstejaars rechtenstudenten.

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