1,958 zoekresultaten voor “humans journal ilmiah ilmu-ilmu humaniora” in de Publieke website
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Phenotypic engineering of photosynthesis related traits in Arabidopsis thaliana using genome interrogation
Promotor: P.J.J. Hooykaas, Co-Promotor: E.J. van der Zaal
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Tail Regeneration in the Tokay Gecko (Gekko gecko)
Regeneration is the ability of an organism to restore damaged or lost tissue with a functional replacement, and without scarring. Many lizards can regenerate their tails.
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Applications for activity-based probes in biomedical research on glycosidases
Lysosomal glycosidases are acid hydrolases that fragment glycoconjugates in lysosomes.
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Visual Relation extraction Based on Deep Cross-media Transfer Network
Building a Deep Cross-media Transfer Network to extract visual relations that relieve the problem of insufficient training data for visual tasks.
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2014
LIBC PUBLIEKSDAG 'HUMAN POTENTIAL; OPTIMALISEER JEZELF, TRAIN JE HERSENEN' (in Dutch)
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A macro level assessment of material circularity
A sustainable resource management is an essential aspect to satisfy the current human needs without compromising the needs of future generations.
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Gene networks-based mechanistic assessment of drug-induced organ toxicity: a focus on liver and kidney
Drug induced organ toxicity is the main problem of the drug development and drug usage in the clinic. The liver and kidneys are the most sensitive organs towards drug induced toxicity.
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Miniaturized metabolomics methods for enabling the study of biomass- restricted samples
This thesis investigated miniaturized mass spectrometry (MS)-based analytical methods to address challenges in analyzing biomass-restricted biological samples.
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Novel analytical approaches to characterize particles in biopharmaceuticals
Particles are omnipresent in biopharmaceutical products. In protein-based therapeutics such particles are generally associated with impurities, either derived from the drug product itself (e.g. protein aggregates), or from extrinsic contaminations (e.g. cellulose fibers).
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CD8+ T-cells in atherosclerosis, recognizing their contribution
Atherosclerosis is the most prominent underlying pathology of cardiovascular disease and an important cause of major adverse cardiovascular events.
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Sensing Transport
Solute carrier (SLC) transporters are a large and diverse class of relatively understudied transmembrane proteins.
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Carcinogenicity of insulin analogues
Promotor: Prof.dr. B. van de Water
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Life In Plastic, Not Always Fantastic: Nano- and microplastics and their impact on terrestrial plants and the food chain
Plastics have become an integral part of modern society due to their versatility and durability.
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Swimming Bass under Pounding Bass: fish response to sound exposure
Promotor: C.J. ten Cate, Co-promotor: H.W. Slabbekoorn
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Advanced in vitro models for studying drug induced toxicity
Promotor: B.van de Water, Co-promotor: L.S.Price
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Environmental footprints: assessing anthropogenic effects on the planet's environment
Promotor: Prof.dr. G.R. de Snoo, Co-promotor: R. Heijungs
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Chitin in the fungal cell wall: towards valorization of spent biomass of Aspergillus niger
Aspergillus niger is an important industrial producer of organic acids and enzymes producing large amounts of spent fungal biomass.
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Asia and the UN
Subproject of the ERC project 'Challenging the Liberal World Order from Within: The Invisible History of the United Nations and the Global South'.
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Bioengineering and biophysics of viral hemorrhagic fever
Viral hemorrhagic fever (VHF) is a group of acute diseases caused by highly infectious viruses including Ebola, Lassa, Dengue viruses. Its high mortality rate poses high risk to public health, however, studies on VHF have been hampered due to the non-availability of proper models and incomplete knowledge…
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Nucleosome stacking in chromatin fibers probed with single-molecule force- and torque-spectroscopy
In human cells, a meter-long DNA is condensed inside a micrometer-sized cell nucleus. Simultaneously, the genetic code must remain accessible for its replication and transcription to functional proteins.
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Metabolomics study of blood vessels-on-chip model
Endothelial dysfunction and microvascular diseases are key drivers of cardiovascular disease, the world's leading cause of death.
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Mast cells as immune regulators in atherosclerosis
Cardiovascular syndromes are the major cause of death in Western societies.
- Onderwijs
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Synthesis of chemical tools to study the immune system
This thesis describes the synthesis and biological evaluation of TLR2/6, TLR4, TLR7/8 and TLR9 ligands, of which the activity can be conditionally controlled.
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Developmental effects of polystyrene nanoparticles in the chicken embryo
There is concern about the threat that nanoplastics (NPs) may pose to both wildlife and humans. This thesis explores the mechanisms of toxicity of polystyrene nanoparticles (PS-NPs) in chicken embryo.
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Virus-host metabolic interactions: using metabolomics to probe oxidative stress, inflammation and systemic immunity
Promotores: T. Hankemeier; R. Berger, Co-promotor: R.J. Vreeken
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Bestrijdingsmiddelen en Milieu
The book ‘Bestrijdingsmiddelen en Milieu' gives a transparent overview of facts and figures concerning pesticide use in the Netherlands and the impact of pesticides on the environment.
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Exploring Grainyhead-like 2 target genes in breast cancer
The objective of this study was to investigate the expression and function of GRHL2 in different breast cancer subtypes.
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AI Labs
AI Labs zijn samenwerkingen van de Universiteit Leiden met externe partner zoals bedrijven, overheidsinstellingen en andere universiteit op het gebied van kunstmatige intelligentie. De Faculteit voor Wis-en Natuurkunde is uniek gesitueerd op het grootste Bioscience Park van Nederlands, en ligt direct…
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Toll-like receptor signaling in the innate immune system of zebrafish larvae
Promotor: H.P. Spaink, A.H. Meijer Co-promotor: R. Marin-Juez
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Algorithms for the description of molecular sequences
Promotor: J.N. Kok, P.E. Slagboom Co-promotor: J.F.J. Laros
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Autophagy and Lc3-associated phagocytosis in host defense against Salmonella
Control of infectious diseases poses continuous challenges for human health.
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Fuzzy systems and unsupervised computing: exploration of applications in biology
In this thesis we will explore the use of fuzzy systems theory for applications in bioinformatics.
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Aria of the Dutch North Sea
Promotores: C. J. ten Cate; M. A. Ainslie. Co-promotor: W. Slabbekoorn
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Advances in GPCR Modeling Evaluated by the GPCR Dock 2013 Assessment: Meeting New Challenges
Source: Structure , Volume 22, Issue 8, pp. 1120-1139 (2014)
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Evolutionary adaptability of β-lactamase: a study of inhibitor susceptibility in various model systems
β-Lactamases are enzymes that can break down β-lactam substrates, such as antibiotics, preventing the use of these antibiotics for the treatment of various infectious diseases. However, some compounds, β-lactamase inhibitors, can block these enzymes allowing for possible treatments using a combination…
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Ecology and genomics of Actinobacteria and their specialised metabolism
Filamentous Actinobacteria, such as Streptomyces, produce a plethora of chemically diverse bioactive metabolites that have found applications across medicine, agriculture and biotechnology.
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The Role of Linker DNA in Chromatin Fibers
The genetic information of all living organisms is contained in their DNA. Cells modify the degree of DNA compaction by epigenetics, which largely determines what genes are read out and which genes are transcriptionally silent.
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De negatieve gevolgen van pesten
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SAILS Workshop Computational Models of Language Learning and Change
Lezing
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SAILS Lunch Time Seminar: Derya Soydaner
Lezing
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Cross-border Resolution of Financial Institutions: Perspectives from International Insolvency Law
In deze publicatie worden problemen met betrekking tot de grensoverschrijdende afwikkeling van financiële instellingen onderzocht.
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Farmacologische conditionering van oxytocine reacties in gezonde vrijwilligers
Is het mogelijk om oxytocine reacties bij gezonde personen farmacologisch te conditioneren en de neurale circuits te identificeren die aan deze conditionering ten grondslag liggen?
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Alexander van OudenhovenWiskunde en Natuurwetenschappen
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Igor DjakovicFaculteit Archeologie
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Karel KuipersFaculteit Archeologie
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Marie SoressiFaculteit Archeologie
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Femke ReidsmaFaculteit Archeologie
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Alexander WilkinsonFaculteit Archeologie
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Amanda HenryFaculteit Archeologie
