1,806 zoekresultaten voor “koninklijke have” in de Publieke website
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Stress-induced modulation of the innate immune system in cardiovascular disease
Promotor: Prof.dr. J. Kuiper
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Data-driven Predictive Maintenance and Time-Series Applications
Predictive maintenance (PdM) is a maintenance policy that uses the past, current, and prognosticated health condition of an asset to predict when timely maintenance should occur.
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Error bounds for discrete tomography
Promotores: K.J. Batenburg, B. Koren
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DNA expressions - A formal notation for DNA
Promotores: J.N. Kok, H.J. Hoogeboom
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The ins and outs of ligand binding to CCR2
Promotor: Prof.dr. A. P. IJzerman, Co-Promotor: L.H. Heitman
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Impact of low-carbon electricity development on carbon emissions in China
Low-carbon (LE) technologies have a significant potential to reduce the total carbon emissions in China.
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Design and development of conformational inhibitors and activity-based probes for retaining glycosidases
Glycosidases are essential in fundamental biological processes and are responsible for the degradation of most (oligo)saccharides, glycolipids and glycoproteins.
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Shaping the pharmacokinetic landscape for renally cleared antibiotics in obesity
The prevalence of obesity (BMI >40 kg/m2) has increased rapidly over the recent years, not only in adults, but also in children and adolescents.
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Resolving the building blocks of galaxies in space and time
We investigate the buildup of galaxies from various vantage points. The first two chapters focus on the stellar content of galaxies, especially the distribution of stellar masses at birth and potential variations therein in various galactic environments.
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Pushing the characterization of exoplanet atmospheres down to temperate rocky planets in the era of JWST
One of the key discoveries in exoplanet research over the past decade is the abundance of small planets in our Milky Way. Despite their high numbers, our understanding of their atmospheres remains limited, and it is unknown if they possess atmospheres at all.
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Plant occurrence in space and time: the importance of land use, habitat structure, and pollination mode
Plant diversity is essential for us and our planet as it sustains the stability of our ecosystems, provides vital materials and food to us and supports many ecosystem services.
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Crossed product algebras associated with topological dynamical systems
Promotor: S.M. Verduyn Lunel, Co-promotoren: M.F.E. de Jeu, S.D. Silvestrov
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From every angle: novel insights into CC chemokine receptor 2 pharmacology
The CC chemokine receptor 2 (CCR2), a member of the G protein-coupled receptor (GPCR) superfamily, is widely involved in autoimmune and inflammatory diseases. However, no drugs for this receptor have made it to the pharmaceutical market yet.
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Improving robustness of tomographic reconstruction methods
Promotor: Prof.dr. K.J. Batenburg
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Patterns of coral species richness and reef connectivity in Malaysia
Promotor: E. Gittenberger, Co-promotor: B.W. Hoeksema
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Orion's Dragon and Other Stories
Stellar feedback is a crucial ingredient in the evolution of galaxies.
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Filter-based reconstruction methods for tomography
Promotor: K.J. Batenburg
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The galaxy–dark matter connection: a KiDS study
In this thesis, the research focuses on the properties of dark matter and dark matter haloes and how they connect with the galaxies we can observe in the Universe.
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Above- and belowground interactions in Jacobaea vulgaris: zooming in and zooming out from a plant-soil feedback perspective
In this thesis, I focused on studying the above- and belowground interactions of J. vulgaris from a plant-soil feedback (hereafter, PSF) perspective. I investigated the temporal variation of negative PSF and examined the effects of root-associated bacteria on plant performance and aboveground herbiv…
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Infrared spectroscopy of astrophysically relevant hydrocarbons
This thesis is about the study of hydrocarbons via infrared spectroscopy.
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The distribution of stellar mass in galaxy clusters over cosmic time
Promotor: Prof.dr. K.H. Kuijken, Co-Promotor: H.Hoekstra
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Mass Spectrometry-Based Degradomics Analysis of Toxoid Vaccines
The chemical and structural heterogeneity of toxoid vaccines makes their analysis challenging. However, detailed insights on a molecular level can be obtained by mass spectrometry.
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Tuning in to star-planet interactions at radio wavelengths
Low-mass main-sequence stars like our Sun are continuous sources of outflowing hot magnetised plasma. In the case of the Sun, this is known as the solar wind, whereas for other stars they are called stellar winds.
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Through the magnifying glass
Although nanoparticles are extensively used in various applications like consumer products and have most probably entered the environment, little is known about the effects of these particles on living organisms.
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Getting personal: Advancing personalized oncology through computational analysis of membrane proteins
Cancer is considered the silent pandemic of the 21st century and the second leading cause of death worldwide.
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A new method to reconstruct the structure from crystal images
Promotor: J.P. Abrahams, Co-promotor: T. Grüne
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Dynamics of the renin-angiotensin aldosterone system in dogs: circadian variations in physiological conditions and in relation to angiotensin-converting
Promotor: Prof.dr. M. Danhof
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The structure of the dusty cores of active galactic nuclei
Promotor: W. Jaffe, Co-promotor: K. Meisenheimer
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Designing Ships using Constrained Multi-Objective Efficient Global Optimization
A modern ship design process is subject to a wide variety of constraints such as safety constraints, regulations, and physical constraints.
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Understanding functional dynamics and conformational stability of beta-glycosidases
Due to their central physiological roles in living organisms, retaining beta-glycosidases have been the subject of tremendous research efforts to examine their structure/function relation using numerous biophysical and biochemical approaches.
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Lights in a sea of darkness: constraining the nature and properties of dark matter using the stellar kinematics in the centres of ultra-faint
Dark matter is one of the biggest mysteries of the Universe. Its properties cannot be explained with the known laws of physics and elementary particles.
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Identification and characterization of developmental genes in streptomyces
Promotor: Prof.dr. G.P. van Wezel
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Human-wildlife Interactions in the Western Terai of Nepal
Large carnivores and humans, along with their livestock, have co-existed for thousands of years. However, human population growth and an increase in economic activities are modifying the landscape for large carnivores and their prey.
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Musems, Collections and Society | Yearbook 2021
In this Yearbook you will find some fascinating examples of what was done in 2021, not only by ourselves, but also by our international colleagues.
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The ecological relevance of chemical diversity in plants
Promotor: P.G.L. Klinkhamer, Co-Promotores: K. Vrieling, P.P.J. Mulder
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Parallel evolution in an invasive plant species: evolutionary changes in allocation to growth, defense, competitive ability and regrowth of invasive
Promotor: Prof.dr. P.G.L Klinkhamer, Co-promotor: K. Vrieling
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Chaotic dynamics in N-body systems
Promotor: Prof.dr. S.F. Portegies Zwart
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Systems vaccinology: molecular signatures of immunity to Bordetella pertussis
Promotor: G.F.A. Kersten, W. Jiskoot, Co-promotor: B. Metz
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Optical Near-Field Electron Microscopy
In this thesis, we develop a novel technique called Optical Near-field Electron Microscopy (ONEM), which aims to combine the advantages of both optical and electron microscopy: the high resolution of electron microscopy and the low sample damage of optical microscopy.
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Interactions from lipid membrane deformations
Biological cells, the basic building blocks of all life forms, are surrounded by a lipid membrane. More than half of the membrane is occupied by membrane proteins, which can regulate the cell functionality through specific arrangements.
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Development of hyaluronan-based dissolving microneedle arrays for dermal vaccination
Dissolving microneedles are a subgroup of microneedle types that completely dissolve within the skin. During this dissolving process the vaccine, stored in the needle matrix, is released into the skin.
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De intieme stem van de Russische Avant-garde: het aanpassen van het esthetische zelf en de opkomst van het Socialistisch Realisme
This proposed research uses ego-documents from visual artists that were not intended for publication to reassess the scholarly debate on the demise of the Russian Avant-garde aesthetic in the twenties and early thirties of the 20th century.
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Anthracycline biosynthesis in Streptomyces: engineering, resistance and antimicrobial activity
Actinobacteria are well known for the production of bioactive natural products, many of which have applications in the fields of human, animal and plant health. Subject of this thesis are the anthracyclines, glycosylated aromatic polyketides with potent anticancer activity.
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Expansions of quantum group invariants
In my research, we developed a method to distinguish knots. A knot is a mathematical depiction of the everyday knot that occurs in ropes and cords.
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Innovation and stasis
The name ‘Jambi flora’ refers to fossil plants found as part of a rock formation from the Early Permian (296 million years old), located in the Jambi Province of Sumatra, Indonesia.
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High-contrast imaging polarimetry of exoplanets and circumstellar disks
Understanding the formation and evolution of planetary systems is one of the most fundamental challenges in astronomy. To directly image and study young exoplanets and the circumstellar disks they form from, dedicated high-contrast imaging instruments are built.
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Novel detectors and algorithms for electron nano-crystallography
Promotor: Prof.dr. J.P. Abrahams, Prof.dr. M. van Heel
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Women Writing Mexico (WWM)
Women Writing Mexico (WWM) is a network of women and men concerned with the human rights crisis in Mexico and more specifically, with the impact of structural forms of poverty, everyday violence, and discrimination based on gender, race, social class, and ethnicity, that particularly have an impact…
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Environmental sustainability of NdFeB magnet recycling: foresight study on recycling systems and technologies
The demand for neodymium-iron-boron (NdFeB) magnets is rapidly growing, while the neodymium supply chain is under pressure. Recycling can alleviate these issues. This thesis investigates the potential for deploying novel magnet recycling technologies and their environmental consequences.
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Big simulations for big problems
In this thesis we investigate cosmology and the large scale structure of the Universe using cosmological simulations.
